نتایج جستجو برای: prodromal angina
تعداد نتایج: 21424 فیلتر نتایج به سال:
Anandamide is a bioactive lipid binding to cannabinoid receptors. A homeostatic role for anandamide has been suggested in schizophrenia. We investigated its role in initial prodromal states of psychosis. We measured the levels of anandamide and its structural analog oleoylethanolamide in cerebrospinal fluid and serum of patients in the initial prodromal state (n=27) alongside healthy volunteers...
CONTEXT A major limitation on the development of biomarkers and novel interventions for schizophrenia is that its pathogenesis is unknown. Although elevated striatal dopamine activity is thought to be fundamental to schizophrenia, it is unclear when this neurochemical abnormality develops in relation to the onset of illness and how this relates to the symptoms and neurocognitive impairment seen...
We compare the reported side effects of medication from the trials of prodromal psychosis treatment. We note that the side effects of antipsychotics are those described in the usual pharmacology of these substances and that the severity of side effects are dependent on dosage, with more side effects at higher doses. We report on the search for alternative compounds for the treatment of prodroma...
BACKGROUND People in a putatively late prodromal state not only have an enhanced risk for psychosis but already suffer from mental and functional disturbances. AIMS To evaluate the acute effects of a combined supportive and antipsychotic treatment on prodromal symptoms. METHOD Putatively prodromal individuals were randomly assigned to a needs-focused intervention without (n=59) or with amis...
Pathophysiological changes of Alzheimer's Disease (AD) begin decades before clinical symptoms become apparent, providing an important window for early diagnosis and intervention. Prodromal stage of AD, a great opportunity for effective treatment and postponing the disease onset, has drawn extensive attention. The application of different biomarkers including neuroimaging, biochemical substances...
Parkinsonism, as a gradually progressive disorder, has a prodromal interval during which neurodegeneration has begun but cardinal manifestations have not fully developed. A systematic direct assessment of this interval has never been performed. Since patients with idiopathic REM sleep behaviour disorder are at very high risk of parkinsonism, they provide a unique opportunity to observe directly...
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