Hepatitis B virus (HBV) is a serious risk as a disease that can be spread through blood transfusion. Occult hepatitis B infection (OBI) is defined in a patient with the presence of HBV-DNA but a lack of HBsAg in the serum and hepatocytes. OBI can be considered as a high potential risk factor for inducing post transfusion hepatitis (PTH), hepatocellular carcinoma (HCC), cirrhosis, and reactivati...

Recent advances in hepatitis research have shed new light on the etiology, pathogenesis, epidemiology and prevention of type B hepatitis infection. The so-called 'Dane' particle is probably the complete hepatitis B virion; its outer coat is the hepatitis B (Australia) antigen (HB Ag) and its inner core is an immunologically distinct particle. Subtypes of HB Ag (a, d, y, w and r) are useful indi...

BACKGROUND Human Immunodeficiency Virus and Hepatitis B virus are blood borne pathogens that can be transmitted through blood transfusion and could pose a huge problem in areas where mechanisms of ensuring blood safety are suspect. This study became necessary in a population where most of the blood for transfusion is from commercial blood donors. METHOD A total of 130 donors comprising 120 co...

Seyed-Moayed Alavian MD 1, Masoud Ahmadzad Asl MD 2, Maryam Keshvari MD 3, Bita Behnava MD 4, Bashir Hajibeigi MD 5 1 Associate Professor of Gastroenterology; Department of Gastroenterology, Baqiyatallah University of Medical Sciences; Dean of Tehran Hepatitis Center, Tehran, Iran 2 Methodology and Statistics Consultant; Nikan Health Researchers Institute, Tehran Hepatitis Center, Tehran, Iran ...

A prospective case control study was carried out to evaluate the prevalence of HBsAg in 129 thalassemic patients and 113 children as a control group.ELISA was used for serologic investigations. thalassemic  patients were aged 8.5+_3.8 years and children of the control group were aged 7.2+_3.8 years.48.1% of the case group and 36.3% of the control group were female and 51.9% of the case group an...

Introduction:Blood-borne infectious agents are one of the main anxieties of Blood Transfusion Organization in all countries. According to WHO, the blood healthy and blood safety is included ensuring and monitoring of quality and efficiency for all patients requiring blood transfusion. We at the current study intend that survey prevalence HIV Ab, HCV Ab, HBS Ag Among blood donors refer to the Bl...

Background: Blood transfusion plays a great role in public health and the blood safety still has remained a main concern. HBV has been considered as one of the most prevalent blood borne infections. It is estimated that chronic HBV affects 350-400 million people worldwide. Comprehensive knowledge about HBV has high importance in Iran due to high number of blood dependent patients. Material ...

CHIBA, S., FUJIWARA, T., SHIONO, H. and NAKAO, T. Frequency of Australia Antigen Detected by Radioimmunoassay in Hepatitis in Children . Tohoku J. exp. Med., 1973, 109 (3), 307-308 Ninety-eight serum specimens obtained from 53 cases of hepatitis in children and 11 specimens from 10 cases of biliary atresia were tested for Australia (Au) antigen by radioimmunoassay (RIA) . Au antigen was detecte...