Transplantation tolerance across histoincompatibilities in multiple non-H-2 minors (B10.BR into CBA/Ca) and "minor" plus H-2D (B10.A into CBA/Ca) antigens has been achieved successfully by combined adult bone marrow transplantation and treatment with CD4 and CD8 mAbs. The tolerant state was confirmed by permanent acceptance of donor strain skin grafts, and in vitro unresponsiveness to donor cel...

      To evaluate the enhancement effect of Berberis vulgaris var. integerrima seeds on the antibacterial activity of cephalexin and ceftizoxime against Staphylococcus aureus and Escherichia coli ethanol extract of the seeds were prepared. Disk diffusion and broth dilution methods were used to determine the antibacterial activity of two cephalosporins in the ...

This research was conducted to determine the efficacy of quizalofop (FirstAct) herbicide in herbicide-tolerant grain sorghum. FirstAct evaluated for and crop response Double Team (ACCase-tolerant) All herbicides controlled Palmer amaranth 90% or more volunteer corn 95% late season. Johnsongrass control 86 91%. Minor sorghum injury early season did not persist. Sorghum receiving postemergence yi...

Two T cell clones, one specific for I-Es/d plus myelin basic protein (BP) and another specific for I-Ak plus influenza virus have been demonstrated to cross-react with DBA/2 cells. Genetic and serological analyses have shown that each clone recognizes its respective priming antigen in association with self-major histocompatibility complex (MHC) determinants and each recognizes DBA/2 minor H ant...

The results presented in this paper demonstrate that responding cells that remain after anti-Ia serum plus complement (C) treatment generate a highly significant in vitro cytotoxic response against minor histocompatibility complex antigens. The cytotoxic response appears to be antigen specific in that target cells of strains other than the sensitizing strain are not lysed, or lysed to a lesser ...

The "70S-associated" 4S RNA from avian myeloblastosis virus contains transfer RNA, as determined by aminoacylation. The various amino acids esterified, plus the great number of minor bases found in this "70S-associated" 4S RNA indicate that a sizeable fraction, but not all, of this RNA is transfer RNA.

BACKGROUND Birth defects (BD) constitute an important public health issue as they are the main cause of infant death. Their prevalence in Europe for 2008-2012 was 25.6 per 1000 newborns. To date, there are no population-based studies for the Russian Federation. The aim of the present study is to estimate the prevalence of BD, its forms, and changes over time in the Russian Arctic city of Monche...

This project works on Bitcoin user categorization and community detection. A new user network generation method is presented to better contract user addresses. Users playing different roles are recognized with K-Means. Three different methods, K-Means, Node2Vector and Fiedler Vector Method are applied to analyze the network community structure. A major radiant community plus a minor community s...

AIMS The aim of this study was to determine whether clopidogrel plus aspirin provides greater protection against major cardiovascular events than aspirin alone in patients with peripheral arterial disease (PAD). METHODS AND RESULTS This is a post hoc analysis of the 3096 patients with symptomatic (2838) or asymptomatic (258) PAD from the CHARISMA trial. The rate of cardiovascular death, myoca...

Recent advances in sequencing technologies have revolutionized genetic studies. Although high-coverage sequencing can uncover most variants present in the sequenced sample, low-coverage sequencing is appealing for its cost effectiveness. Here, we present AbCD (arbitrary coverage design) to aid the design of sequencing-based studies. AbCD is a user-friendly interface providing pre-estimated effe...