نتایج جستجو برای: pharmacological
تعداد نتایج: 74572 فیلتر نتایج به سال:
Although all-trans retinoic acid (RA) induces complete remission in a high proportion of patients with acute promyelocytic leukemia (APL), all groups have described clinical relapses despite continued RA treatment. This finding suggests that resistance to the cytodifferentiating effects of the retinoid had been acquired. To investigate potential mechanisms of clinical resistance to RA, we seria...
Fabry disease is an inherited lysosomal storage disorder caused by deficient α-galactosidase A activity. Many missense mutations in Fabry disease often cause misfolded gene products, which leads to their retention in the endoplasmic reticulum by the quality control system; they are then removed by endoplasmic reticulum-associated degradation. We discovered that a potent α-galactosidase A inhibi...
OBJECTIVE To review baboon syndrome (BS). DATA SOURCES Date sources were obtained from PubMed and Google Scholar: Photographs of baboon syndrome were obtained from our patient. STUDY SELECTIONS PubMed and Google Scholar were searched up to June 30, 2010. The search terms were "baboon syndrome", "SDRIFE" and "thimerosal allergy". Reverse references from relevant articles and Google Scholar w...
Introduction: ‘Restless Legs Syndrome’ is a sensory-motor disorder manifested by a tendency to move legs, usually accompanied by discomfort in the legs. Studies have shown that diabetics are more at risk for Restless Legs Syndrome than the general population. Therefore, a review study was designed to determine the methods of controlling restless legs syndrome in patients with diabetes. Methods:...
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