BACKGROUND Periodontitis is one of the most common oral diseases associated with the host's immune response against periodontopathogenic infection. Failure to accurately diagnose the stage of periodontitis has limited the ability to predict disease status. Therefore, we aimed to look for reliable diagnostic markers for detection or differentiation of early stage periodontitis using the immunopr...

While many point-of-care (POC) diagnostic methods have been developed for blood-borne analytes, development of saliva-based POC diagnostics is in its infancy. We have developed a portable microfluidic device for detection of potential biomarkers of periodontal disease in saliva. The device performs rapid microfluidic chip-based immunoassays (<3-10 min) with low sample volume requirements (10 mi...

OBJECTIVE Chronic periodontitis is the most common form of periodontal disease. Chang- es in biomarkers seem to be associated with the disease progression. Procalcitonin (PCT) is one of these biomarkers that are altered during infection. This study was established to investigate the relationship between periodontitis as an infectious disease and salivary PCT. MATERIALS AND METHODS This case-c...

BACKGROUND AND OBJECTIVE A low-grade systemic inflammatory status originating from periodontal infection has been proposed to explain the association between periodontal disease and systemic conditions, including adverse obstetric outcomes. The aim of this study was to evaluate the effect of periodontal therapy during pregnancy on the gingival crevicular fluid and serum levels of six cytokines ...

Periodontal diseases such as gingivitis and periodontitis are considered common diseases. This study is aimed to predicate these using non-harmful specimens saliva throughout the detection of some parameters. In beginning, a random 51 patients' was collected from outpatients who suffered different degrees periodontal Concurrently, another 40 people appeared be healthy were collected, both patie...

Bacterial endocarditis is the infection of inner lining of heart and /or heart valves. This disease is usually related to the presence of some pathogenic bacteria in mouth, digestive system or urinary tract. Most of the times, this infection happens in people with heart problems like the presence of prosthetic valves, history of previous endocarditis, some congenital heart defects and heart tra...

Introdouction: Cone Beam Computed Tomography (CBCT) is a relatively new three-dimensional imaging technology, which has been widely used in dental and maxillofacial imaging. Materials and methods: CBCT scans of 506 maxillary sinuses of 253 individuals (39.9% male and 60.1% female) were evaluated retrospectively for assessing the relationship between sinus mucosal thickening (MT) and dental a...

Background & Aims: Metabolic syndrome is composed of interrelated cardiovascular and cardiometabolic risk factors. Moreover, recent researches have illustrated the association of systemic diseases and periodontitis. Thus, the early diagnosis of this syndrome, as a cardiometabolic risk factor, seems necessary. The aim of this study was to evaluate the prevalence of metabolic syndrome in patients...