Some time ago we demonstrated the acetylation of S-benzyl-L-cysteine in the dog, rabbit, rat, and man (l-3). Administration of S-benzyl-ncysteine to rats (4, 5) or man (3) was followed by the excretion of some N-acetyl-S-benzyl-L-cysteine, thus indicating a partial inversion of the D derivative of cysteine to the optical antipode. Ample experimental evidence is available to show that oxidative ...

Key words nickel catalysis - deamination cross-coupling unnatural peptides amino acid pyridinium salts

1. Halobacterium cutirubrum L-alanine dehydrogenase was purified approx. 100-fold. 2. It has a mol. wt. of 72 500, about one-third that of two well-studied alanine dehydrogenases from non-halophiles. 3. The activity of the enzyme increases with temperature up to 70 degrees C, but the protein itself is not thermostable. 4. In the reductive amination reaction, the enzyme is fully active in the pr...

drogenase in normal human skin. In comparison with glutamate dehydrogenase, which catalyzes reversible oxidative deamination, the transaminases catalyze transfer of amino groups, usually from an amino acid to a ketoacid, without net loss of nitrogen. In other words, transamination represents the intermolecular exchange of amino nitrogen. Transamination plays a significant role in metabolism by ...