نتایج جستجو برای: osteochondral defect
تعداد نتایج: 97437 فیلتر نتایج به سال:
INTRODUCTION Osteochondral grafts have become popular for treating small, isolated and full-thickness cartilage lesions. It is recommended that a slightly oversized, rather than an exact-sized, osteochondral plug is transplanted to achieve a tight fit. Consequently, impacting forces are required to insert the osteochondral plug into the recipient site. However, it remains controversial whether ...
BACKGROUND Numerous treatment methods for osteochondral repair have been implemented, including auto- and allogeneic osteochondral transplantations, combined bone and chondrocyte transplantations, and synthetic implants, but no gold standard treatment has been established. We present preliminary data on a combined autologous bone and cartilage chips: autologous dual-tissue transplantation (ADTT...
OBJECTIVE To investigate the utility of bone-marrow-derived mononuclear cells (BMNCs) and insulin like growth factor-1 (IGF-1) in articular cartilage repair. DESIGN An osteochondral defect of 3 mm diameter and 5 mm depth was created in patellar groove of the left knee joint in each of 36 New Zealand White rabbits. The defect was filled with RPMI-1640 medium in group A (control), autologous BM...
Case. This case report describes the operative management of 16-year-old male with a symptomatic chondroblastoma of the distal femur with breach of the chondral surface. Following appropriate imaging and core needle biopsy, the diagnosis was confirmed histologically. The patient then underwent intralesional curettage and osteochondral allograft reconstruction of the defect. At one-year follow-u...
Focal articular cartilage injuries in the knee are common and can cause severe morbidity and reduced function. The articular cartilage is avascular and has limited ability to heal, and hence, patients with cartilage injuries have increased risk of progressing to osteoarthritis. Most of the cartilage injuries are located on the femoral condyles. Engaging focal cartilage injuries involving the tr...
BACKGROUND Full-thickness defects measuring 3 mm in diameter have been commonly used in studies of rabbits to evaluate new procedures designed to improve the quality of articular cartilage repair. These defects initially heal spontaneously. However, little information is available on the characteristics of repair of larger defects. The objective of the present study was to define the characteri...
OBJECTIVES We sought to determine if a durable bilayer implant composed of trabecular metal with autologous periosteum on top would be suitable to reconstitute large osteochondral defects. This design would allow for secure implant fixation, subsequent integration and remodeling. MATERIALS AND METHODS Adult sheep were randomly assigned to one of three groups (n = 8/group): 1. trabecular metal...
Osteochondral defects of the femoral head are rare and principles of treatment include anatomic reduction, rigid fixation, enhancement of blood supply, and restoration of articular congruity. In this report, we present a case where the defect of the femoral head was treated with surgical dislocation of hip anteriorly and mosaicplasty. At 3-year follow-up, the patient was symptom free with...
Defects in articular cartilage can be repaired through osteochondral transplantation (mosaic arthroplasty), where osteochondral plugs from non-weight-bearing areas of the joint are transferred to the defect site. Incongruity between the plug surface and the adjacent cartilage results in increased contact pressures and poorer outcomes. We compare three methods to predict the desired repair surfa...
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