24 Review Article ORAL SUBMUCOUS FIBROSIS: AN UPDATE ON ETIOLOGY AND PATHOGENESIS-A REVIEW Shukla A, Singh A, Srivastava R Abstract: Oral submucous fibrosis (OSMF) is a chronic disease of oral mucosa characterized by inflammation and progressive fibrosis followed by stiffening of an otherwise yielding mucosa resulting in difficulty in opening the mouth. It is generally accepted today that areca...

This article describes a male patient who presented with trismus due to submucous fibrosis and how in course of time it turned malignant into oral squammous cell carcinoma. Oral submucous fibrosis (OSF) is a chronic, complex, irreversible, highly potent pre-cancerous condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (lamina prop...

Several studies have suggested that low socioeconomic status (SES) is associated with a higher risk of oral cancer, but the association with oral premalignant lesions has not yet been explored. The aim of this study was to examine the association of education, occupation, income and SES index with oral premalignant lesions. A case-control study was conducted with data from the baseline screenin...

It is a challenge to simultaneously reconstruct bilateral buccal defects following oral cancer ablation or release of oral submucous fibrosis. In this study, we report two cases where bipaddled anterolateral thigh perforator flaps were used to resurface two separate buccal defects.

Oral submucous fibrosis (OSF) is a chronic, insidious disease. The presence of autoantibodies in sera of OSF patients is the most characteristic and direct evidence of OSF being an autoimmune disease. To identify the specific autoantigens which could contribute to antibody production, the Human Proteome Microarrays composed of 19000 full-length unique proteins were employed. 45 proteins correla...