Abstract Objective The purpose of this clinical trial was to examine the effect omega-3 fatty acids (W-3 FAs), nanocurcumin and their combination on serum levels gene expression VCAM in patients with episodic migraine. Results In study, 80 were randomly divided 4 groups receive for 2 months. Both showed remarkable decreases after single W-3 combined interventions. However, a borderline signific...