Many long noncoding RNAs are bound to chromatin. MEG3 binds to multiple different genomic locations, containing GA-rich motifs, and form RNA-DNA triplex structures. In this work, we test whether the MEG3 binding sites are specific enough to be regulated by a particular lncRNA. We show that at least in the case of MEG3, a subset of the triplex target sites (TTS) is able to hybridize with various...

Abstract Feedback is important to improve writing quality; however, provide timely and personalized feedback a time-intensive task. Currently, most literature focuses on providing (human or machine) support product characteristics, especially after draft submitted. However, this does not assist students who struggle during the process. Therefore, in study, we investigate use of keystroke analys...

In the present study fungi collections were sampled in the Sangay (SP) and Llanganates (LP) National Parks, from which sequences of the regions of the internal transcribable spacer (ITS1-5.8S-ITS2) of the ribosomal DNA were obtained (RDNA). The taxonomic identification of fungi of the order Xylariales was achieved with the bioinformatic tools, to further study the phylogenetic relationships amo...

In the present study fungi collections were sampled in the Sangay (SP) and Llanganates (LP) National Parks, from which sequences of the regions of the internal transcribable spacer (ITS1-5.8S-ITS2) of the ribosomal DNA were obtained (RDNA). The taxonomic identification of fungi of the order Xylariales was achieved with the bioinformatic tools, to further study the phylogenetic relationships amo...

Angina bullosa hemorrhagica (ABH) is a benign disorder of the oral cavity. Clinically, oral, blood-filled blisters are seen. To give a proper diagnosis, one should rule out any other cause. We aim to present this case in order to emphasize this rare cause of oral bullae which is necessary to be differentiated from many serious dermatological and hematological disorders. Salih Levent Cinar ( ) C...

Seasonal flu vaccine is recommended as the best protection for cancer patients against influenza infection. Recent and experimental data in silico suggest that antibodies elicited with influenza vaccine could activate bradykinin receptor B2-associated signaling pathway, which is also involved in cell proliferation and migration of tumor cells. These results point to an urgent need for the ree...

Ecuador has a great variety of climatic regions that potentiate biodiversity. The family constitutes one of the most important of the country, having Orchidaceae identified about 4032 species with a high degree of endemism, therefore the development and research of alternative methods of storage and conservation of species is a strategy of primary interest for researchers and for society in gen...

This paper discusses the parallel writing tradition in East Asian languages and its representation in metadata. Parallel writing systems in these languages do not use the same scripts, but they all share a common scheme and have a well-established tradition in bibliographic data. Their data representation in the MARC bibliographic format is handled in a variety of ways. Even in the metadata wor...

Angina bullosa hemorrhagica (ABH) is a benign disorder of the oral cavity. Clinically, oral, blood-filled blisters are seen. To give a proper diagnosis, one should rule out any other cause. We aim to present this case in order to emphasize this rare cause of oral bullae which is necessary to be differentiated from many serious dermatological and hematological disorders. Salih Levent Cinar ( ) C...

In this paper, we propose a method for assisting amateur writers in novel writing. Amateur writers can publish their work intensively through web infrastructures. This situation is beneficial, because it encourages amateur writers to enhance their skills by sharing their work. However, writing a good novel is difficult for a novice, because the novel-writing task requires the management of many...