نتایج جستجو برای: mck
تعداد نتایج: 210 فیلتر نتایج به سال:
Having abundant natural resources, the village is foundation of city. Villages have potential to develop various natural, physical, social, demographic, and cultural resources that not been optimally utilized. Therefore, sustainable development necessary improve villagers' welfare quality life. This study aims identify status sustainability sensitive attributes in through a case Cijeruk Village...
Stupka N, Schertzer JD, Bassel-Duby R, Olson EN, Lynch GS. Calcineurin-A activation enhances the structure and function of regenerating muscles after myotoxic injury. Am J Physiol Regul Integr Comp Physiol 293: R686–R694, 2007. First published May 2, 2007; doi:10.1152/ajpregu.00612.2006.—Calcineurin signaling is essential for successful muscle regeneration. Although calcineurin inhibition compr...
OBJECTIVE Transgenic expression of diacylglycerol acyltransferase-1 (DGAT1) in skeletal muscle leads to protection against fat-induced insulin resistance despite accumulation of intramuscular triglyceride, a phenomenon similar to what is known as the "athlete paradox." The primary objective of this study is to determine how DGAT1 affects muscle fatty acid oxidation in relation to whole-body ene...
Basic helix-loop-helix (bHLH) regulatory proteins are known to bind to a single DNA consensus sequence referred to as an E-box. The E-box is present in the regulatory elements of many developmentally controlled genes, including most muscle-specific genes such as troponin I (TnI). Although the E-box consensus is minimally defined as CANNTG, the adjacent nucleotides of functional E-boxes are vari...
Ophthalmology Research Laboratories, Burns & Allen Research Institute, Cedars-Sinai Medical Center, UCLA Medical School Affiliate, Los Angeles, California (AVL,ZH,GHH,MCK); MGH/Harvard Cutaneous Biology Research Center, Massachusetts General Hospital East, Charlestown, Massachusetts (REB); Department of Animal Physiology, Uppsala University, Uppsala, Sweden (DG); Renal Division, Washington Univ...
A prominent problem in Graph Theory is to find extremal graphs or digraphs with restrictions in their diameter, degree and number of vertices. Here we obtain a new family of digraphs with minimal diameter, that is, given the number of vertices and out-degree there is no other digraph with a smaller diameter. This new family is called modified cyclic digraphs MCK(d, `) and it is derived from the...
Skeletal muscle insulin resistance is a major characteristic of obesity and type 2 diabetes. Although obesity-mediated inflammation is causally associated with insulin resistance, the underlying mechanism is unclear. Here, we examined the effects of chronic obesity in mice with muscle-specific overexpression of interleukin-10 (MIL10). After 16 weeks of a high-fat diet (HFD), MIL10 mice became m...
There is no effective treatment for the cardiomyopathy of the most common autosomal recessive ataxia, Friedreich ataxia (FA). This disease is due to decreased expression of the mitochondrial protein, frataxin, which leads to alterations in mitochondrial iron (Fe) metabolism. The identification of potentially toxic mitochondrial Fe deposits in FA suggests Fe plays a role in its pathogenesis. Stu...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید