BACKGROUND Executive control of cognition, emotion, and behavior are disrupted in the manic state of bipolar disorder. Whereas frontal systems are implicated in such dysfunction, the localization of functional brain abnormalities in the manic state is not well understood. METHODS We utilized a high-sensitivity H(2)(15)0 positron emission tomography technique to investigate regions of increase...

Dysfunctional thought patterns are presumed to underlie cognitive biases in mood disorder patients. However, few studies have compared dysfunctional thought patterns in bipolar manic and unipolar depressed patients. Cognitive schemas and dysfunctional attitudes were evaluated using the cognitive checklist for mania and Dysfunctional Attitudes Scale (DAS) in 34 bipolar manic, 35 unipolar depress...

The unusual feature of this case was the development of manic stupor. Although this condition is described in classical texts (e.g. Hamilton. 1974). in clinical practice most psychiatrists never see a case in their lifetime. It is seldom easy to make the diagnosis prospectively Usually, several differential diagnoses are entertained, including neuroleptic malignant syndrome, for such patients h...

BACKGROUND Bipolar disorders (BD) are of particular public health significance as they are prevalent, severe and disabling, and often associated with elevated risks of premature mortality. The aim of this concise overview is to investigate the role of asenapine in the treatment of manic and mixed states associated with BD type 1 disorder. METHOD MedLine, Excerpta Medica and PsycINFO searches ...

The assumption that female manic-depressives have similar personality characteristics to those reported for male manic-depressives was tested. Besides using previously employed self-report measures from which personality attributes related to conformity and value achievement have been inferred, a peer conformity experiment was carried out. 16 remitted female manicdepressives were matched with 1...

The separation of manic depressive illness from schizophrenia was an important diagnostic task undertaken early on by Kraepelin (1896, 1919) who saw schizophrenia (“dementia praecox”) as a psychotic illness and a thought disorder, characterised by a steady downhill in cognition leading to chronic dementia, whereas manic depressive illness was seen as an episodic affective disorder with intermit...

Development of manic symptoms during treatment with atypical antipsychotics can be a troublesome side effect that has been described with most atypical antipsychotics. However, reports of amisulpride induced mania have been rare. Here, we report the case of an 18-year-old male patient diagnosed with schizophrenia, who developed manic symptoms while on treatment with amisulpride. While previous ...