Cyanosis, clubbing, and arterial oxygen desaturation may occur in patients with liver disease, and are attributed to the presence of pulmonary or peripheral arterio-venous shunting. Cardiac catheterisation and angiocardiography in a patient with a normal heart did not demonstrate the presence of abnormal arterio-venous anastomoses. Pulmonary shunting was proved when intravenous technetium-label...

BACKGROUND To investigate the role of upper extremity radionuclide venography as a potential diagnostic modality in the assessment of venous thrombosis associated with a Port-A catheter. METHODS Fourteen symptomatic patients who had received Port-A catheter implantation were enrolled. A dynamic nuclear medicine flow study was performed with intravenous administration of Technetium-99m macroag...

THE PYRAMIDAL LOBE IN THYROID IMAGING J' L. Izenstark, A.L.ForsaithandN. H. Horwitz 519 MEASUREMENT OF FLOW THROUGH BRANCHED SYSTEMS USING EXTERNAL RADIATION DETECTORS Stephen W. Thompson 525 DETERMINATION OF SERUM THYROXINE BY SATURATION ANALYSIS OF THYROXINE BINDING PROTEINS Aifredo CuarÃ3n 532 BABOON KIDNEY EXCRETION OF 203Hg-CHLORMERODRIN DURING ISOLATED BLOODLESS PERFUSION G. S. Johnston, ...

Lung perfusion study is an important investigation in various pulmonary diseases. The radiopharmaceutical commonly used now-a- days is imported macroaggregated human albumin (in kit form), which is labelled with technetium (Tc99m-MAA). Due to its high cost the technique could not be fully exploited. We have tried to locally prepare freeze dried MAA particles. Various parameters like concentrati...

Pulmonary scintigraphy has a well-established role in the diagnosis of pulmonary embolism (PE). The diagnostic specificity is increased if the perfusion study is combined with assessment of regional ventilation. VQ scans interpreted as either normal, near-normal, or high probability are reasonably diagnostic. Misinterpretation of the VQ scan can result in failure of this simple and noninvasive ...

BACKGROUND For yttrium-90 ((90)Y) radioembolization, the common practice of assuming a standard 1,000-g lung mass for predictive dosimetry is fundamentally incongruent with the modern philosophy of personalized medicine. We recently developed a technique of personalized predictive lung dosimetry using technetium-99m ((99m)Tc) macroaggregated albumin (MAA) single photon emission computed tomogra...

A LeVeen peritoneo-venous shunt is placed for intractable ascites. Determination of obstruction site in the shunt tube is a difficult problem. We describe a simple nuclear medicine method using 111MBq (3mCi) of Technetium-99m labeled macro-aggregated albumin injected intraperitoneally.

UNLABELLED Indium-111-labeled macroaggregated albumin (MAA) would be suitable for combined pulmonary perfusion and ventilation scan using a 99mTc ventilation agent. METHODS MAA suspended in 0.1 M sodium acetate buffer, pH 5.8, was incubated with 111In-chloride for 30 min at room temperature. An in vitro study of the obtained 111In-MAA was performed for labeling efficiency and stability in hum...

UNLABELLED Planning hepatic (90)Y radioembolization activity requires balancing toxicity with efficacy. We developed a dual-tracer SPECT fusion imaging protocol that merges data on radioactivity distribution with physiologic liver mapping. METHODS Twenty-five patients with colorectal carcinoma and bilobar liver metastases received whole-liver radioembolization with resin microspheres prescrib...