The prevalence of cocaine adulterated with levamisole-induced vasculitis is increasing and physicians should be aware of this unique entity. There have been many reports of cutaneous vasculitis syndrome caused by cocaine which is contaminated with levamisole. Levamisole was used as an antihelminth drug and later was rescinded from use in humans due to adverse effects. Through this paper, we wil...

The effects of supplementing diets with levamisole on growth, immune response and resistance against pathogenic Aeromonas hydrophila were determined. Fish were assigned to three treatments with different level of levamisole (125, 250 and 500 mg kg ̄1 diet) and the control diet was prepared without levamisole. Cirrhinus mrigala were fed at 4% of their body mass for 60 days. Growth performance, en...

OBJECTIVE To assess the efficacy of levamisole in frequently relapsing nephrotic syndrome and steroid-dependent nephrotic syndrome. STUDY DESIGN Retrospective analysis of hospital case records. SETTING Pediatric nephrology department of a tertiary referral pediatric hospital. PARTICIPANTS 62 children with frequently relapsing nephrotic syndrome and 35 children with steroid-dependent nephr...

Paraherquamide is a novel natural anthelmintic product with a mode of action that is incompletely characterized. Nicotine and cholinergic-anthelmintic agonists of different chemical classes were used to produce contraction in Ascaris muscle strips. Paraherquamide and a semisynthetic derivative, 2-deoxy-paraherquamide, antagonized these responses. Analysis of the actions of the antagonists was m...

A double-blind study was carried out to investigate the possibility of therapeutic effect of levamisole on recurrent progenital herpes. One hundred and nine patients, including 53 females, entered the study, but only 75 completed. Levamisole, 50 mg three times daily for 3 days, was started at the first sign of recurrence. The study period consisted of 6 visits or 12 months, whichever came first...

The United States Public Health Service Substance Abuse and Mental Health Services Administration is alerting medical professionals that a substantial percentage of cocaine imported into the United States is adulterated with levamisole, a veterinary pharmaceutical that can cause blood cell disorders such as severe neutropenia and agranulocytosis. Levamisole HCl is the active ingredient in a num...

INTRODUCTION Hepatitis B virus (HBV) infection is much more common in hemodialysis patients than the general population. Up to half of hemodialysis patients do not have adequate protective HBV antibodies after HBV vaccination. We studied the effects of adding levamisole, as an immunomodulator and adjuvant agent, on seroconversion response to HBV vaccination in hemodialysis patients. MATERIALS...

The neurotoxic effects of levamisole therapy have been rarely reported. In this article, we report two patients who developed multifocal demyelinating leukoencephalopathy (MDL) after levamisole treatment. Clinically, they had dizziness, nausea, vomiting, confusion, mental dullness, speechlessness, and memory impairment after the treatment. The total dosage of levamisole was 300 mg and 1800 mg, ...

The comparative efficacy of 2 anthelmintics (ivermectin and levamisole) against Baylisascaris transfuga migrating and encapsulated larvae was studied in mice. A total of 60 BALB/c mice inoculated each with about 1,000 embryonated B. transfuga eggs were equally divided into 6 groups (A-F) randomly. Mice of groups A and B were treated with ivermectin and levamisole, respectively, on day 3 post-in...