Lightweight Expanded Clay Aggregate (LECA), a clay-based lightweight aggregate expanding after burning at high temperatures, is among the promising material since it can be used as construction materials for buildings and roads, geotechnical fillings, hydroponic growing medium, humidity control, wall damper, heat insulation, water treatment, others. However, potential of clay from various place...

PARENTE is a user-friendly software package that conducts parentage inference using molecular data from diploid codominant markers. Based on the principle of genetic compatibility, PARENTE looks for maternity, paternity, or simultaneously for both potential parents, using multilocus genotypes and birth and death dates of individuals (if available). It also calculates the probability of successf...

The possibility of Pb2+, Cd2+, Ni2+ and Ba2+ ions removal from aqueous solution using light expanded clay aggregate (LECA) was investigated in this work. central composite design (CCD) response surface methodology (RSM) used to optimize the operating parameters (adsorbent granulometry, absorption time initial metal concentration) reach maximum single multi-elemental solutions. After optimizatio...

Steroid and hopanoid biomarkers can be found in ancient rocks may give a glimpse of what life was present at that time. Sterols hopanoids are produced by two related enzymes, though the evolutionary history this protein family is complicated losses horizontal gene transfers, appears to widely misinterpreted. Here, I have added sequences from additional species, re-analysis phylogeny SHC OSC ind...

The synthesis of phenylene-ethynylene rods and their use as rigid spacers is described. Alternation of a Sonogashira reaction and silyl group cleavage was used to obtain rigid spacers with even and odd numbers of phenylene units. Preliminary applications of these rods in divalent systems are shown. Inhibition studies with Pseudomonas Aeruginosa lectin LecA showed that the rigid spacer proved gr...

All living organisms require protein degradation to terminate biological processes and remove damaged proteins. One such machine is the 20S proteasome, a specialized barrel-shaped and compartmentalized multicatalytic protease. The activity of the 20S proteasome generally requires the binding of regulators/proteasome activators (PAs), which control the entrance of substrates. These include the P...

Protein-coding genes in eukaryotes are interrupted by introns, but intron densities widely differ between eukaryotic lineages. Vertebrates, some invertebrates and green plants have intron-rich genes, with 6-7 introns per kilobase of coding sequence, whereas most of the other eukaryotes have intron-poor genes. We reconstructed the history of intron gain and loss using a probabilistic Markov mode...

Cancer disease is inherent to, and widespread among, metazoans. Yet, some of the hallmarks of cancer such as uncontrolled cell proliferation, lack of apoptosis, hypoxia, fermentative metabolism and free cell motility (metastasis) are akin to a prokaryotic lifestyle, suggesting a link between cancer disease and evolution. In this hypothesis paper, we propose that cancer cells represent a phenoty...

P. aeruginosa produces two lectins: PA-IL (LecA) (that bind galactose [Gal] and L-arabinose [Ara]), and PA-IIL (LecB) (that binds fucose [Fuc] > mannose [Man] and fructose [Fru]) [5,6]. These lectins contribute to the pathogens adhesion to target cells [7] and amplify the destructive effects of their accompanying virulence factors on those cells [8]. They also contribute to the pathogen auto-ag...