Introduction Lupus nephritis (LN) is one of the main clinical presentations determining the course and outcome of systemic lupus erythematosus (SLE) in children. It occurs in 40–80% of pediatric patients at presentation and can be even higher during the later stages of the disease. The severity of the disease varies from mild glomerulonephritis to severe manifestations leading to end-stage rena...

Le régime fasciste a accordé une place essentielle à sa politique extérieure en Méditerranée et Afrique. Sous-tendue par la construction de projets domination, elle fut étroitement liée l’idéologie aux structures internes du régime. L’historiographie eut pourtant tendance pendant assez longtemps (1945-an. 1970) sous-évaluer l’importance couper ses liens avec les dynamiques fascisme. Inauguré da...

Glioma is one of the most common malignant brain tumors. Current chemotherapy is far from providing satisfactory clinical outcomes for patients with glioma. More efficient drugs are urgently needed. Artesunate (ART) is clinically used as an anti-malarial agent and exhibits potent antiproliferative activity as a traditional Chinese medicine. In addition, ART has been shown to exert a profound cy...

BACKGROUND Pentoxifylline (PX) is a methyl xanthine derivative that influences the sperm motion characteristics and L-carnitine (L-C) is an amino acid that is naturally produced in the body. In general, separate administration of PX and L-C has been reported to be effective on preserving sperm motility in vitro, and also when is consumed orally by the Idiopathic oligoasthenoteratozoospermia (IO...

An artificial neural network (ANN) is an information-processing paradigm that is designed to emulate some of the observed properties of the mammalian brain. First proposed in the early 1950's it was not until the technology revolution of the 1980's that a multitude of alternative ANN methods were spawned to solve a wide variety of complex real-world problems. Today, the contemporary literature ...

BACKGROUND To date, antiretroviral therapy (ART) guidelines and programs in resource-limited settings (RLS) have focused on 1(st)- and 2(nd)-line (2 L) therapy. As programs approach a decade of implementation, policy regarding access to 3(rd)-line (3 L) ART is needed. We aimed to examine the impact of maintaining patients on failing 2 L ART on the accumulation of protease (PR) mutations. METH...