Objectives To investigate the efficacy and safety of intravitreal dexamethasone (OZURDEX®) implantation in patients with recalcitrant diabetic macular edema. Materials and Methods This is a retrospective non-randomized study of patients who underwent intravitreal dexamethasone implantation for recalcitrant diabetic macular edema. Main outcome measures included changes in best corrected visual...

to determine the prognostic value of response to treatment in patients with focal segmental glomerulo-sclerosis. fsgs includes 10-15% of idiopathic nephrotic syndrome in children. bulk of evidence supports disease relationship with immune system. unfortunately, responses to immunosuppressive drugs are not desirable and progression to end-stage renal disease is common. we analyzed 62 out of 99 c...

We report a 64-year-old diabetic woman who developed neovascularization of the posterior capsule 2 years after cataract surgery and intraocular lens implantation. The patient was treated with single injection of 1.25 mg of intravitreal bevacizumab (Avastin) via pars plana. After one week, complete regression of the posterior capsule neovascularization was achieved allowing us to perform Nd: YAG...

OBJECTIVES To describe the classification, clinical features, and evaluation of diabetic retinopathy and to review its conventional as well as most updated management. DATA SOURCES Literature search of Medline up to October 2006. STUDY SELECTION Key words for the literature search were 'diabetic', 'retinopathy', 'treatment', 'laser photocoagulation', 'vitrectomy', 'corticosteroid', 'protein...

Introduction: Because of bilateral involvement in many cases with diabetic macular edema, Intravitreal bevacizumab injection perform in both eyes. There are some reports of therapeutic effects in the fellow eye after monocular injection of anti-vascular endothelial growth factors. In this study we describe a case of bilateral improvement of diabetic macular edema following unil...

PURPOSE To investigate the diagnostic value of a topical dexamethasone (DXM) provocative test before intravitreal triamcinolone acetonide (IVTA) injection for a steroid response. METHODS Eligible patients scheduled for first-time IVTA who did not have glaucoma or a history of a steroid response received DXM 0.1% drops 4 times daily over 4 weeks. After that, IVTA was given except in DXM respon...

of blindness among the elderly. In the US, more than eight million people suffer from this disease; this number is projected to increase many-fold by 2020.1 AMD can be of the dry and wet form and is a consequence of excessive aging associated with alterations in the retinal pigment epithelium (RPE). In wet AMD, CNV occurs with fluid build-up in the sub-retinal space. The dry form of AMD is asso...