نتایج جستجو برای: hypovolemia

تعداد نتایج: 1126  

Journal: :The Journal of pharmacology and experimental therapeutics 1999
P De Paepe F M Belpaire G Van Hoey P A Boon W A Buylaert

The influence of hypovolemia (removal of 30% of the blood volume) on the pharmacokinetics and pharmacodynamics of etomidate was investigated in the rat. Chronically instrumented animals were randomly allocated to either a control (n = 9) or a hypovolemia (n = 9) group, and etomidate was infused (50 mg/kg/h) until isoelectric periods of 5 s or longer were observed in the electroencephalogram. Th...

2014
Morten Zaar Chriselda G. Fedyk Heather F. Pidcoke Michael R. Scherer Kathy L. Ryan Caroline A. Rickards Carmen Hinojosa-Laborde Victor A. Convertino Andrew P. Cap

Central hypovolemia elevates hemostatic activity which is essential for preventing exsanguination after trauma, but platelet activation to central hypovolemia has not been described. We hypothesized that central hypovolemia induced by lower body negative pressure (LBNP) activates platelets. Eight healthy subjects were exposed to progressive central hypovolemia by LBNP until presyncope. At basel...

Journal: :American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2014

2015
Takafumi Nishizaki Norio Ikeda Shigeki Nakano Takanori Sakakura Natsumi Fujii Tomomi Okamura

Objective: Use of an epidural self-blood patch (EBP) is the most effective form of therapy for patients with cerebrospinal fluid (CSF) hypovolemia. However, even if the symptoms are resolved, other clinical aspects of this condition frequently prevent patients resuming social activity. In the present study, we investigated the clinical course of patients with CSF hypovolemia after treatment wit...

Journal: :Anesthesiology 2010
Claes U Wiklund Denis R Morel Hélène Orbring-Wiklund Jacques-Andre Romand Vincent Piriou Jean-Louis Teboul Karim Bendjelid

BACKGROUND Sensitivity and specificity of respiratory change in pulse pressure (DeltaPP) to predict preload dependency has been questioned at small tidal volumes (VT) in critically ill patients suffering from acute respiratory distress syndrome (ARDS). We studied DeltaPP in pigs with ARDS-like syndrome during reversible hemorrhagic shock. METHODS Prospective, observational animal study in a L...

Journal: :Journal of the Canadian Association of Gastroenterology 2021

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