The present paper reviews the findings accumulated on the role of pineal gland and its hormone - melatonin - in regulation of the hypothalamo-neurohypophysial system activity. Effects of modified photoperiod, pinealectomy or treatment with melatonin on the vasopressin and oxytocin biosynthesis and/or secretion have been described. Taken together, the in vivo and in vitro data suggest that the e...

Cushing syndrome (CS) is an endocrinological disorder characterized by increased blood cortisol level. It either due to excessive endogenous release of steroids (e.g., pituitary adenoma or adrenal hyperplasia) exogenous administration steroids. Iatrogenic the most common form syndrome. The vast majority cases are oral parenteral steroid preparations, which commonly prescribed for pulmonary, ren...