BACKGROUND In diabetes, a variety of pro-inflammatory cellular changes has been found in various cell types, including monocytes which are known to be involved in all the phases of atherogenesis. Angiotensin II (Ang II) type 1 receptor (AT1R) mediates the pro-atherogenic effects of Ang II whereas the type 2 receptor (AT2R) seems associated with atheroprotection. We sought to investigate the pot...

Background and Aims: A transient increase of blood concentration of lipids after meal is able to increase the risk of atherogenesis. This study aimed to determine the effects of Anethum graveolens L. (dill) consumption on atherosclerosis and hepatic risk factors. Methods: In an experimental study, 32 male New Zealand rabbits were randomly allocated to four groups to receive normal diet, a d...

Increased plasma cholesterol is known to be a major risk related to the development of coronary artery disease. The main purpose of this study was to determine possible effects of the ethanolic extract of aerial parts of Peucedanum pastinacifolium on the serum lipids in hypercholesterolemic rats. Experimental hypercholesterolemia was induced by feeding rats ???? ????????????????????????????...

Increased plasma cholesterol is known to be a major risk related to the development of coronary artery disease. The main purpose of this study was to determine possible effects of the ethanolic extract of aerial parts of Peucedanum pastinacifolium on the serum lipids in hypercholesterolemic rats. Experimental hypercholesterolemia was induced by feeding rats ???? ????????????????????????????...

OBJECTIVE To determine the efficacy of nicotinic acid on the lipid profile of diabetic and non diabetic rats. METHODS This was an experimental study done at the Institute of Molecular Biology and Biotechnology, The University of Lahore, Pakistan between May 2010 to July 2010. Nicotinic acid was administered to a hypercholesterolemic group and a hypercholesterolemic + diabetic Group of Albino ...

To explore the protective effect of sesame seed oil (SSO) extracted from Til-06 variety in Sprague-Dawley male rats against management hypercholesterolemia, current two-phase study was conducted. In first phase, taken out seeds (Til-06) and physicochemical analysis carried to find content following by evaluation quality attributes oil. second efficacy check hyperlipidemic activity Randomly dist...

BACKGROUND Coronary heart disease is the leading cause of mortality worldwide. A high-fat diet, rich in saturated fatty acids and low in polyunsaturated fatty acids, is said to be an important cause of atherosclerosis and cardiovascular diseases. METHODS In this experimental study, 40 male rabbits were randomly assigned to eight groups of five to receive normal diet, hypercholesterolemic diet...

The present study aimed to investigate the anti-hyperlipidemic effects of sesame in a high-fat fed rabbit model. Animals were randomly divided into four groups of eight animals each for 60 days as follows: normal diet, hypercholesterolemic diet (1% cholesterol), hypercholesterolemic diet (1% cholesterol) + sesame seed (10%), and hypercholesterolemic diet (1% cholesterol) + sesame oil (5%). Seru...

N-nitrosodiethylamine (NDEA) is an important carcinogen frequently present in human environment and food chain. Nitrosamines such as NDEA produce oxidative stress due to generation of reactive oxygen species and alter the antioxidant defence system in the tissues. The present investigation was aimed at studying its toxicity under hypercholesterolemic conditions. NDEA administration brought abou...