Eosinophilia in tissues and/or circulating blood is known to be associated with a wide variety of malignancies but the role of the eosinophil in neoplastic conditions is not known. Using the cheek pouch of the Syrian hamster as an experimental model for oral carcinogenesis, it has recently been shown that eosinophils at sites of developing oral cancer express the multifunctional cytokine, trans...

A major obstacle to successful oral vaccination is the lack of antigen delivery systems that are both safe and highly efficient. Conventional replication-incompetent adenoviral vectors, derived from human adenoviruses of subgroup C, are poorly efficient in delivering genetic material to differentiated intestinal epithelia. To date, 51 human adenovirus serotypes have been identified and shown to...

The aim of this study was to determine the degree to which the epidermis and oral epithelium of species other than man express cytokeratin (CK) intermediate filaments, which are markers of epithelial differentiation. Fixed, wax-embedded samples of skin, buccal mucosa and gingiva from rhesus monkey, marmoset, cow, sheep, pig, ferret, hamster, axolotl and trout were tested for CK expression using...

The oral cavity is a complex environment. It serves as a portal between the outside and the inside of an organism. It is the primary organ regulating what is or is not allowed to enter the gut as food. It performs the ¢rst line of food selection (by physical feel and chemical taste) and processing (by mechanical and enzymatic breakdown). It also performs the additional functions of speech and e...

Background: Human beta-defensins (hBDs) are small cationic peptides of the epithelium with broad antimicrobial and immune response-regulatory activities. hBDs also related to oncogenesis, their secretion profiles affected by radiotherapy treatment. The present study aimed investigate oral cavity hBD 1-3 levels in head neck cancer patients its relation Methods: Sixteen (all a history smoking) we...

Differentiation of epiglottal epithelia during human development was for the first time investigated by the light microscopy and documented in celoidine collection of human embryos from the Archive of the Department of Histology and Embryology, School of Medicine University of Zagreb, Croatia. At 6 weeks epiglottal swelling was found to be covered by a simple squamous epithelium consisting of a...

PURPOSE To determine the expression of differentiation and progenitor cell markers in corneal tissues that previously underwent autologous cultivated oral mucosal epithelial transplantation (COMET). METHODS Four eyes from three alkaline-injured patients and one thermally injured patient underwent COMET to promote re-epithelialization or corneal reconstruction. Between 10 and 22 months (mean, ...

human papilloma virus causes benign and malignant abnormalities in different part of the body. the link between high risk types of hpv and some anogenital and aerodigestive tract cancer is well established. oral hpv infection plays a role in developing oropharyngeal squamous cell carcinoma. we studied the prevalence of oral hpv in healthy individuals and its relative risk factors.saliva samples...

introduction: oral lichen planus (olp) and oral lichenoid lesions (olls) are clinically and histopathologically similar lesions but with different etiologies and treatment plan, thus differentiatingthese two has been the center of many researches. studies in different populations have beenperformed on clinical and histopathologic features of olp and olls. thus aim of the present studywas to eva...