I (ummins D, Heuischkcl R, Davies S. P'enicillin prophylaxis in children with sickle cell disease in 13rent. BAIJ 1991;302: 989-9(0. (27 April.) 2 Ferguson AD, Scott RB. Studies in sicklc cell anaemia. XIII. The management olt pneumonia in childrenl with sickle cell anemia. ,Medical Annals of the District of Columbil 1958;27:636-4 1. 3 Warlcy MA, Hamilton P'JS, Marsden PI), Brown RE, Miersellis...

background: we aimed to determine the incidence of co-inheritance as well as interaction of sickle cell trait (sct) and α thal /β thal mutations in south and south central of iran. method: we employed a pcr and restriction fragment length polymorphism techniques to confirm diagnosis of sickle cell trait. all subjects were screened for any α/β -thalassemia mutations using a gap-polymerase chain ...

objective(s) sickle cell disease is a genetic disorder characterized by chronic haemolytic anaemia. haemoglobin s containing red blood cells may be susceptible to oxidative stress due to imbalance between production of reactive oxygen species and the countering effect of the various antioxidants present in the body. materials and methods we evaluated some antioxidant enzymes which include gluta...

Xmn1 polymorphism is a known factor, which increases fetal haemoglobin production. Among the inherited disorders of blood, thalassaemia and Sickle Cell Diseases contributes to a major bulk of genetic diseases in India. Our aim was to verify the role of the Xmn1 polymorphism as a modulating factor in sickle cell patients and frequency of the polymorphism in Indian sickle cell patients. 60 sickle...