Feed restriction may be a strategy used by farmers to limit digestive disorders after weaning. The objective of this study was to evaluate the effect of feed restriction applied 1 wk after weaning on growth performance and health of pigs reared in 2 different sanitary conditions (Good vs. Poor; managed in opposite ways with respect to cleaning, animal density, and preventive antibiotic use) and...

The accessibility of hemoglobin sulfhydryl groups to modification by p-mercuribenzoate @"B) was tested in order to investigate the effect of the hemoglobinhaptoglobin association on the contact between a and /3 chain subunits. Previous evidence indicates that a molecule of tetrameric hemoglobin binds to haptoglobin as two separate a& dimers. Modification of the hemoglobin a and B chain sullhydr...

A student had haemoglobin in the urine after running but not after cycling. The haemoglobinuria was related to the hardness of the surface on which he ran and to his running style. The concentration of haptoglobin in his plasma was less than normal. This was most pronounced after he had been running, when haptoglobin had combined with free haemoglobin, but the concentration was also low when th...

not found. The serum bilirubin was 0.7 mg./iOO ml., the alkaline phosphatase x6 K.A. units/ioo ml. and the flocculation tests were normal. In the xylose absorption test, 5 g. xylose were excreted in the urine in five hours. A three day test of fat excretion in the stools showed an average of 2.8 g./24 hours. Progress Nine days after admission the h2emoglobin had fallen to 7.2 g./ioo ml., the wh...

The haptoglobin phenotypes of 3,332 individuals, consisting of 2,930 caucasians and 402 negroes living in the greater Boston area, were determined. Of these, 3,222 were hospitalized medical patients fully documented regarding diagnoses. One hundred and twentyeight of the total population studied were shown to exhibit starch gel anhaptoglobinaemia (3.7%). Re-evaluation on acrylamide gel of 118 0...

Human hemoglobin (Hb) and haptoglobin (Hp) exhibit an extremely high affinity for each other, and the dissociation of Hb tetramers into dimers is generally believed to be a prerequisite for complex formation. We have investigated Hp interactions with native Hb, αα, and ββ cross-linked Hb (ααXLHb and ββXLHb, respectively), and rapid kinetics of Hb ligand binding as well as the redox reactivity i...

In Brief Prospective identification of individuals with diabetes who are at greatest risk for developing complications would have considerable public health importance by allowing appropriate resources to be focused on those who would benefit most from aggressive intervention. Haptoglobin (Hp) is an acute-phase protein that is crucial for the elimination of free hemoglobin and the neutralizatio...

The binding of liganded hemoglobin to haptoglobin, a plasma cr2-glycoprotein, is an irreversible and stoichiometric reaction that occurs physiologically at the micromolar concentration level. The study of the reaction between deoxyhemoglobin which does not bind haptoglobin and a haptoglobin solution saturated with carbon monoxide indicates that hemoglobin tetramer is incapable of binding haptog...

The immunoelectrophoretic patterns of plasma proteins from mice are altered significantly by acute infections. Some proteins are dissociated into two or more components, some showed striking increase in plasma concentration, others are depleted, and certain ones appear which are undetectable in normal samples. beta(1)-C dissociated into two electrophoretic components under a variety of conditio...