نتایج جستجو برای: gastric acid anti
تعداد نتایج: 1166721 فیلتر نتایج به سال:
OBJECTIVE To investigate the preventive and therapeutic effects of Danshen Decoction on gastric ulcer in experimental animal models. METHODS The model of water immersion restraint stress ulcer in mice, and the models of acetic acid impaired gastric ulcer and pyloric ligation gastric ulcer in rats were established. The total gastric acid, the activity of pepsin and the amount of gastric wall b...
The present study was performed to evaluate the anti-ulcerogenic activity of hyaluronic acid against ethanol induced gastric mucosal injury in rats. Four groups of adult Sprague Dawley rats were orally pretreated respectively with distilled water (ulcer control groups), omeprazole (reference group), high molecular weight hyaluronic acid and 0.8% hyaluronic acid gel (experimental groups) one hou...
objective(s) gastric ulceration is induced by various forms of stress like surgery, ischemia and trauma. the female sex has more resistance to stress and the gastrointestinal lesions happen fewer than male sex. the purpose of this study was to evaluate the role of estradiol and progesterone on the gastric acid and pepsin levels following traumatic brain injury (tbi) induction. materials and met...
background: gastric cancer is the fourth common malignancy and the second prevalent cause of cancer death in the world. genetic and environmental factors play an important role in the development of this cancer. nutritional and epidemiological studies have indicated that folate status modulates the risk of developing cancer and apoptosis has been reported to play a decisive role in precancerous...
The compound 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) is an efficient anion exchanger inhibitor that can block the activities of anion exchanger 2 (AE2), which plays an indispensable role in gastric acid secretion. DIDS also has potent anti-oxidative and antiapoptosis activities. This study aimed to investigate the effect of DIDS on ethanol-induced mucosal damage in rats and to e...
Helicobacter pylori is involved in gastritis, gastric and duodenal ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. Earlier studies already suggested a role for autoimmune phenomena in H. pylori-linked disease. We now report that lipopolysaccharides (LPS) of H. pylori express Lewis y, Lewis x, and H type I blood group structures similar to those commonly occurring...
Aspirin and nonsteroidal anti-inflammatory agents are known to induce gastroduodenal complications such as ulcer, bleeding, and dyspepsia. In this study, we examined the prophylactic effect of rebamipide, an anti-ulcer agent with free-radical scavenging and anti-inflammatory effect, on acidified aspirin-induced gastric mucosal injury in rats. In addition, we investigated the mucosal barrier fun...
It has been reported that many anti-inflammatory drugs employed in the treatment of rheumatic disorders cause various gastrointestinal disturbances , such as haemorrhage and the development or reactivation of peptic ulcer . The mechanisms involved are not understood precisely, but they may include stimulation of gastric acid secretion and de crease in the resistance of the local gastrointestina...
Gastric ulcer is one of the most common chronic gastrointestinal diseases characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H. pylori) infection and the frequent long-term use of non-steroidal anti-inflammatory drugs are major factors involved in gastric ulcer development. Acid inhibitors and antibiotics are commonly used to treat gastric ulcer. However, in the ...
Various pharmacological effects including anti-inflammatory and anti-oxidant properties were shown for woody endocarpium of walnut alcoholic extract (WEW). In the study, effect WEW in acetic acid induced ulcerative colitis rats was evaluated. Thiol, glutathione peroxidase (GPX), malondialdehyde (MDA), superoxide dismutase (SOD) gastric levels pathological changes colon investigated control grou...
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