Brain CT has become a standard imaging tool for emergent evaluation of brain condition, and measurement of midline shift (MLS) is one of the most important features to address for brain CT assessment. We present a simple method to estimate MLS and propose a new alternative parameter to MLS: the ratio of MLS over the maximal width of intracranial region (MLS/ICWMAX). Three neurosurgeons and our ...

In the aerospace sector the products complexity clearly highlights the need to manage a wide variety of technologies in evolving and changeable scenarios. A way to successfully govern this multiplicity is by designing products thoughtfully integrated and ready to operate in scenarios that grow more and more entangled by the day. Fully embracing an integrated Systems Engineering (SE) approach is...

OBJECTIVES Infancy is a critical stage of life, and a secure relationship with caring and responsive caregivers is crucial for healthy infant development. Early parenting interventions aim to support families in which infants are at risk of developmental harm. Our objective is to systematically review the effects of parenting interventions on child development and on parent-child relationship f...

DSTC’s model transformation tool, Tefkat, is an implementation of a declarative transformation language proposed in reposonse to the OMG’s MOF 2.0 QVT RFP. The language contains several distinct features aimed specifically at enabling re-use and enhacing the maintainability of large transformation specifications. In this position paper we describe these features, how they contribute to the lang...

The International Agency for Research on Cancer (IARC) reported meta-analyses of the association of cutaneous malignant melanoma (CMM), finding significant correlations with ever use of sunbeds and first use of sunbeds prior to age 35 years; it did not claim that the associations showed causal links. However, some observational studies in the meta-analysis included individuals in the UK with sk...

Specifying queries on models is a prerequisite to model transformations in the MDA because queries select the model elements that are the source of transformations. Current responses to OMG's MOF 2.0 QVT RFP mostly propose to use (and/or extend) OCL 2.0 as specification language for queries. In this paper, we demonstrate that using textual notations (like OCL) quickly leads to complex query sta...

epidemiology studies have demonstrated inconsistent associations between type 2 diabetes mellitus and the risk of malignant melanoma. to this end, the aim was to perform a meta-analysis of cohort studies.medline, pubmed, embase and the cochrane library were searched up to february 2014. cohort studies addressing the relative risk of type 2 diabetes mellitus on malignant melanoma were included i...

The use of meta-analysis in medicine is widespread nowadays, particularly in the field of interventional cardiology. Meta-analysis is a statistical approach aiming to combine date from a large number of patients from randomized clinical studies and/or non-randomized registries so as to obtain a pooled estimate of the results and to answer specific research questions. It is important to take the...

task assignment problem (tap) involves assigning a number of tasks to a number of processors in distributed computing systems and its objective is to minimize the sum of the total execution and communication costs, subject to all of the resource constraints. tap is a combinatorial optimization problem and np-complete. this paper proposes a hybrid meta-heuristic algorithm for solving tap in a h...