Polyamines (PAs) are low molecular weight metabolites involved in various physiological and developmental processes in eukaryotic and prokaryotic cells. The cellular PA level is regulated in part by the action of amine oxidases (AOs) including copper diamine oxidases (DAOs) and flavoprotein polyamine oxidases (PAOs). In this study, the isolation and characterization of flavin amine oxidases (FA...

FAO maintains endothelial permeability 3 Abbreviations: EC endothelial cell FAO fatty acid oxidation TCAc tricarboxylic acid cycle FA fatty acid iMAT integrative metabolic analysis tool GSMM genome-scale metabolic network model SILAC stable-isotope labeling with amino acids in cell culture HUVEC human umbilical vein endothelial cells ECM extracellular matrix TEER trans-endothelial electrical re...

15 Fatty acid oxidation (FAO) is essential for oocyte maturation in mice. The objective of this 16 experiment was to determine the effect of etomoxir (a FAO inhibitor; 100 μM), carnitine (1 17 mM), and palmitic acid (1 or 100 μM) during maturation on metabolism and gene expression of 18 the oocyte and cumulus cells, and subsequent embryo development in the mouse. Carnitine 19 significantly incr...

The correlations between intramyocellular lipid (IMCL), decreased fatty acid oxidation (FAO), and insulin resistance have led to the hypothesis that impaired FAO causes accumulation of lipotoxic intermediates that inhibit muscle insulin signaling. Using a skeletal muscle-specific carnitine palmitoyltransferase-1 KO model, we show that prolonged and severe mitochondrial FAO inhibition results in...

During activation, T cells undergo metabolic reprogramming, which imprints distinct functional fates. We determined that on PD-1 ligation, activated T cells are unable to engage in glycolysis or amino acid metabolism but have an increased rate of fatty acid β-oxidation (FAO). PD-1 promotes FAO of endogenous lipids by increasing expression of CPT1A, and inducing lipolysis as indicated by elevati...

Enabling environments for agribusiness and agro-industries development Regional and country perspectives The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) concerning the legal or development status of any country, territory, ...

The pyfao56 software package is a Python-based implementation of (1) the American Society Civil Engineers (ASCE) Standardized Reference Evapotranspiration Equation and (2) Food Agricultural Organization United Nations (FAO) Irrigation Drainage Paper No. 56 (FAO-56) dual crop coefficient methodology. was initially developed to support water use estimation irrigation scheduling for field research...

The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations (FAO) or of the World Health Organization (WHO) concerning the legal or development status of any country, territory, city or area or of its authorities, or concerning the delimitat...

Traditionally, potatoes are a central component of warm meals in many European countries (Wandel et al. 2001; FAO, 2004). In an analysis from the EPIC study (n 13 031 men and 22 924 women) including data from ten European countries (Greece, Spain, Italy, France, Germany, The Netherlands, UK, Denmark, Sweden and Norway), potatoes contributed on average 7 % to the total carbohydrates consumed, bu...