The present paper summarizes selected results of the first author‟s Master‟s thesis for the student track at the 10th International Conference on Wirtschaftsinformatik in Zurich, Switzerland. The thesis was co-supervised by the second and the third author. Building upon the technology acceptance model (TAM), the assignment was to investigate factors impacting on end users‟ acceptance of enterpr...

Activation of hepatic stellate cells (HSCs) and subsequent uncontrolled accumulation of altered extracellular matrix (ECM) underpin liver fibrosis, a wound healing response to chronic injury, which can lead to organ failure and death. We sought to catalogue the components of fibrotic liver ECM to obtain insights into disease etiology and aid identification of new biomarkers. Cell-derived ECM wa...

The mechanical properties of tumors and the tumor environment provide important information for the progression and characterization of cancer. Tumors are surrounded by an extracellular matrix (ECM) dominated by collagen I. The geometrical and mechanical properties of the ECM play an important role for the initial step in the formation of metastasis, presented by the migration of malignant cell...

Breast cancer progression involves genetic changes and changes in the extracellular matrix (ECM). To test the importance of the ECM in tumor cell dissemination, we cultured epithelium from primary human breast carcinomas in different ECM gels. We used basement membrane gels to model the normal microenvironment and collagen I to model the stromal ECM. In basement membrane gels, malignant epithel...

The sandwich culture of hepatocytes, between double layers of extra-cellular matrix (ECM), is a well-established in vitro model for re-establishing hepatic polarity and maintaining differentiated functions. Applications of the ECM-based sandwich culture are limited by the mass transfer barriers induced by the top gelled ECM layer, complex molecular composition of ECM with batch-to-batch variati...

The strongly nonlinear switching kinetics of electrochemical metallization memory (ECM) cells are investigated using an advanced 1D simulation model. It is based on the electrochemical growth and dissolution of a Ag or Cu filament within a solid thin film and accounts for nucleation effects, charge transfer, and cation drift. The model predictions are consistent with experimental switching resu...

We employed linear and nonlinear error correction models (ECMs) to predict the log returns of Bitcoin (BTC). The ECM is best model for predicting BTC compared neural network autoregressive in terms RMSE, MAE, MAPE. Using a ECM, we are able understand how affected by other coins. In addition, performed Granger-causality tests on fourteen cryptocurrencies.

This report serves two purposes: To introduce and validate the Execution-Cache-Memory (ECM) performance model and to provide a thorough analysis of current Intel processor architectures with a special emphasis on Intel Xeon HaswellEP. The ECM model is a simple analytical performance model which focuses on basic architectural resources. The architectural analysis and model predictions are showca...

Angiogenesis is regulated by the local microenvironment, including the mechanical interactions between neovessel sprouts and the extracellular matrix (ECM). However, the mechanisms controlling the relationship of mechanical and biophysical properties of the ECM to neovessel growth during sprouting angiogenesis are just beginning to be understood. In this research, we characterized the relations...