Stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type I diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. In addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...

In endodontics, treatment of an open apex tooth with necrotic pulp is a problem. It seems that with promotion of remnants of Hertwig's epithelial sheath or rest of malassez accompany with a good irrigation of root canal we can expect root formation. (Iranian Endodontic Journal 2008;3:42-43).

The inflammatory answer of the dental pulp in front of an antigen presents a series of particularities caused by its special anatomical conditions. The evaluation of the inflammatory answer in the evaluation tests of the biocompatibility of the dental materials is made by histological methods without defining precise quantitative criteria to measure the pulp reaction. In this study, we followed...

Orthodontic force may lead to cell damage, circulatory disturbances, and vascular changes of the dental pulp, which make a hypoxic environment in pulp. In order to maintain the homeostasis of dental pulp, hypoxia will inevitably induce the defensive reaction. However, this is a complex process and is regulated by numerous factors. In this study, we established an experimental animal model of or...

STATEMENT OF THE PROBLEM Pulp stones are calcifications found in the pulp chamber or pulp canals of the teeth. Its different prevalence in different population is a matter of concern. PURPOSE This study aimed to assess the prevalence of pulp stones in a sample of Iranian population and to report its occurrence regarding gender, dental arch, tooth type and dental status. MATERIALS AND METHOD...

BACKGROUND Different methods have been used in order to isolate dental pulp stem cells. The aim of this study was to study the effect of different types of pulp treatment during isolation, under 3% O2 conditions, in the time needed and the efficacy for obtaining dental pulp stem cells. MATERIAL AND METHODS One hundred and twenty dental pulps were used to isolate dental pulp stem cells treatin...

Dental pulp represents a specialized connective tissue enclosed by dentin and enamel, the most highly mineralized tissues of the body. Consequently, the direct examination as well as pathological evaluation of dental pulp is difficult. Within this anatomical context, our study aimed to evaluate the correlation between dental pulp lesions and clinical diagnosis. Pulpectomies were performed for 5...

Odontogenic cysts are pathological cavities enclosed by fibrous connective tissue and lined with epithelial that develops from odontogenic tissues in the maxilla mandible's tooth-bearing regions. Trauma or tooth caries is main cause of radicular periapical cysts. Pulp necrosis outcome dental irritating pulp cavity. Once infection has reached root's tip, it causes periodontitis, which may lead t...

Avulsion injury is one of the most severe types traumatic dental injuries. Following avulsion, periodontal ligament tissues are injured and vessels nerves pulp rupture at apical foramen which causes necrosis. In studies it was reported that key to retention knocked-out teeth maintain viability ligament. Storage media plays an important role in preserving PDL cells during extra alveolar time. Th...

Capík I . , V. Ledeck ̆, A. ·evãík: Effects of Flumetazone on Exposed Dental Pulp of Dogs. Acta Vet. Brno 2003, 72: 279-283. Dental pulp metabolism plays very important role throughout the tooth life. Its role is essential particularly in the first two-three years. This is the time of the highest dentin deposition which provides sufficient firmness to withstand common everyday trauma. This study...