In 6 dogs, experiments were performed to determine the tissue reaction of the dental pulp at the 7, 30 and 60 days after direct contact of the pulp with the obturation material through a microcommunication orifice with diameter up to 1 mm, formed in the fundic part of an experimental cavity. Capping of 36 mandibular premolars with traumatically exposed pulp was carried out. On the exposed pulp,...

Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world's population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality making it prone for secondary infections. Over the past decade, several tissue-engineering ...

Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and extracellular matrix molecules forming the specialized microenvironment of dental pulp stem cell niches. Here we study the activation of putative pulp ni...

External Cervical Resorption in maxillary canines with pulp vitality is frequently associated with dental trauma resulting from surgical procedures carried out to prepare the teeth for further orthodontic traction. Preparation procedures might surgically manipulate the cementoenamel junction or cause luxation of teeth due to applying excessive force or movement tests beyond the tolerance limits...

Background: Pulp stones are calcification in the dental pulp which can be present either in deciduous or permanent teeth. Exact causes of pulp stones are not known and several elements have been associated. It can be seen in healthy, diseased or as a part of various syndromes. Frequency of pulp stones fluctuated from 8 to 95% depending on the population studied. Our study is an attempt to know ...

i ntroduction: the aim of this study was to evaluate the clinical and histological status of the pulp in sound human premolars after direct pulp capping (dpc) with four different dpc methods/materials. methods and materials: this study was conducted on eight volunteers who had to extract four first premolars due to orthodontic treatment. subsequent to tooth isolation, standardized class i occlu...

The objective of this study was to determine the effects of Prevotella intermedia, Fusobacterium nucleatum and Lactobacillus casei on the production of IL-8 by human dental pulp cells. Human dental pulp cells from teeth of young patients (aged 18-25 years) were cultured and tested with sonicated P. intermedia ATCC 25611, F. nucleatum ATCC 25586 and L. casei ATCC 4646 extracts. IL-8 secreted int...

Sixty-three vital permanent incisors with complicated crown fractures were treated by partial pulpotomy and assessed clinically and radiographically for healing. Healing of the pulp was considered to have taken place when the following criteria were fulfilled: absence of clinical symptoms, radiographic evidence of dentin bridge formation, no intrapulpal or periapical pathosis, continued root de...

Damaged dental pulp undergoes oxidative stress and 4-hexylresorcinol (4HR) is a well-known antioxidant. In this study, we aimed to evaluate the therapeutic effects of 4HR ointment on damaged pulp. Pulp cells from rat mandibular incisor were cultured treated with or resveratrol (1–100 ?M). These treatments (10–100 ?M) exerted protective effect during subsequent hydrogen peroxide treatments. The ...