An improved physics-informed neural network (IPINN) algorithm with four output functions and physics constraints, which possesses neuron-wise locally adaptive activation function slope recovery term, is appropriately proposed to obtain the data-driven vector localized waves, including solitons, breathers rogue waves (RWs) for Manakov system initial boundary conditions, as well parameters discov...

introduction: the aim of this study was evaluate the ability of notochord to induce neural induction and/or differentiation of mouse embryonic stem cell to neuron and motor neuron, respectively. methods: in order to produce embryoid bodies, es cells line royan b1 were grown in suspension in the absence of lif for 4 days. ebs were divided into 4 groups. ebs in group 1 & 2 were further cultured i...

Circuit-level implementation of a novel neuron has been discussed in this article. A low-power Activation Function (AF) circuit is introduced in this paper, which is then combined with a highly linear synapse circuit to form the neuron architecture. Designed in Carbon Nanotube Field-Effect Transistor (CNTFET) technology, the proposed structure consumes low power, which makes it suitable for the...

The slice patch clamp technique is a powerful tool for investigating learning-induced neural plasticity in specific brain regions. To analyze motor-learning induced plasticity, we trained rats using an accelerated rotor rod task. Rats performed the task 10 times at 30-s intervals for 1 or 2 days. Performance was significantly improved on the training days compared to the first trial. We then pr...

OBJECTIVES Silver nanoparticles (Ag-NPs) are used widely in bedding, water purification, tooth paste and toys. These nanoparticles can enter into the body and move into the hippocampus. The aim of this study was to investigate the neurotoxicity of silver nanoparticles in the adult rat hippocampus. MATERIALS AND METHODS 12 male Wistar rats were randomly divided into two experimental and contro...

objective(s): the main characteristic of mesenchymal stem cells (mscs) is their ability to produce other cell types. electromagnetic field (emf) stimulates differentiation of mscs into other cells. in this study, we investigated whether emf can effect on the differentiation of mscs into dopaminergic (da) neurons. materials and methods: an emf with a frequency of 50 hz and two intensities of 40 ...

background: alzheimer’s disease (ad) is characterized by progressive neuronal loss in hippocamp. epidermal neural crest stem cells (epi-ncsc) can differentiate into neurons, astrocytes and oligodendrocytes. the purpose of this study was to evaluate the effects of transplanting epi-ncsc into ad rat model. methods: two weeks after induction of ad by injection of amyloid-β 1-40 into ca1 area of ra...

there is strong evidence demonstrating that nifedipine dissolved in ethanol selectively inhibits only l-type ca2+ current. in addition, acute ethanol exposure reduces voltage-dependent calcium currents. in the present study, we investigated the antagonistic effect of fixed concentration of nifedipine dissolved in different concentration of ethanol on l-type ca2+ current. in a na+-k+ free soluti...