objective: the study aimed to determine the relationship between presence of antiphospholipid antibodies (apls) and clinical pregnancy rate in patients undergoing ivf/icsi procedures. materials and methods: this descriptive-analytic study performed on two hundred consecutive women referred for ivf/icsi in vali-e-asr reproductive health research center. serum levels of apls , anticardiolipin [ac...

The aim of this study was to assess the sperm quality and testicular histomorphometry of Wistar rats supplemented with extract and fractions of fruits of Tribulus terrestris L. The ethanolic extract was obtained by dynamic maceration of spray-dried fruit. This extract was fractionated by liquid-liquid partition, using increasing polarity solvents. Twenty male rats were separated in four groups,...

A cell extract derived from human parainfluenza virus type 3-infected human lung carcinoma (HLC) cells synthesized mRNA in vitro. Under optimal conditions, the extract was able to support transcription of all virus-encoded genes as determined by hybridization analyses. The RNA products contained full-length poly(A)-containing mRNA species similar to those observed in acutely infected cells. Fur...

Genomic reprogramming factors in the cytoplasm of germinal vesicle (GV) stage oocytes have been shown to improve the efficiency of producing cloned mouse offspring through the exposure of nuclei to a GV cytoplasmic extract prior to somatic cell nuclear transfer (SCNT) to enucleated oocytes. Here, we developed an extract of GV stage pig oocytes (GVcyto-extract) to investigate epigenetic reprogra...

Mung bean (Vigna Radiata) has been traditionally used in China both as nutritional food and herbal medicine against a number of inflammatory conditions since the 1050s. A nucleosomal protein, HMGB1, has recently been established as a late mediator of lethal systemic inflammation with a relatively wider therapeutic window for pharmacological interventions. Here we explored the HMGB1-inhibiting c...

Incubation of HeLa cells at 24 degrees C results in the modification of the processing of pre-tRNA to tRNA. Both methylation and size reduction were shown to take place in vitro when purified pre-tRNA was subjected to processing in a cytoplasmic extract of HeLa cells The migration of pre-tRNA from the nucleus to the cytoplasm was not significantly altered at 24 degrees C

Background and Objective: Diabetes causes fertility disorders by interfering with the endocrine gland function. There are reports that, green tea and catechins could have anti-oxidant and hypoglycemic properties. Therefore, in the present study, we evaluated the effects of green tea aqueous extract and catechin influence on pituitary-gonadal axis in rat models of type 1 diabetes. Materials & M...

Cancer remains to be a major global healthcare burden as 18.1 million new cases and 96 death occurred 2018 on the basis of report from international agency for research cancer Breast is most common diagnosed in women causing highest morbidity. Ipomoea carnea leaf extracts have been used chemotherapeutic agent due their antioxidant, anti-inflammatory, anti-bacterial, anti-tumor effect. The aim s...