A study was undertaken to compare the efficacy of three drugs in the treatment of uncomplicated strongyloidiasis in Okinawa, Japan. Two hundred and eleven patients with confirmed Strongyloides stercoralis infection were given either ivermectin, 6 mg in a single dose, albendazole, 400 mg/day for 3 days or pyrvinium pamoate, 5 mg/kg/day for 3 days. For each treatment, the same regimen was repeate...

A second polymorphic form of a 1 : 2 : 3 pamoate : DABCO : water salt has been obtained by liquid-assisted grinding, and it is shown that interconversion between this salt and a salt with 1 : 1 : 2 stoichiometry is facile via liquid-assisted grinding with additional amounts of pamoic acid (to generate the 1 : 1 : 2 salt) or DABCO (to generate the 1 : 2 : 3 salt).

n engl j med 370;20 nejm.org may 15, 2014 1954 transmitted helminth infections: systematic review and metaanalysis. JAMA 2008;299:1937-48. 3. Keiser J, Tritten L, Silbereisen A, Speich B, Adelfio R, Vargas M. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis 2013;7(3):e2119. 4. Nagpal S, Sinclai...

This study was concerned with changes in the auditory canal and its associated structures in rats as affected by aging and by oral administration of tià ̄s(p-aminophenyl)carbonium pamoate (TACP). Multiple sections of tissue blocks from the auditory canal area were reviewed in control and treated animals of both sexes, and of varying ages up to 18 months. Tumors were found in the auditory canal g...

Accepted: 05/09/2013 Abstract Twenty four lions of Nandankanan Zoo were studied for prevalence of nematode eggs by faecal sample analysis and the prevalence rate was found to be 70%. For evaluation of anthelmintics, 20 lions were considered and were divided into four groups according to the drug administered and each group consisted of five animals. The lions were administered pyrantel pamoate ...