statement of problem: biomechanics of the human dentition is inherently complex. purpose: the aim of this study is to investigate, in vitro, the creep and the recovery of dentin under static uniaxial compressive stress conditions. materials and methods: specimens of cylindrical morphology were prepared from recently extracted non-carious lower molar teeth, such that the average tubule orientati...

In this article, the axisymmetric mechanical buckling of thin cylindrical shell made of functionally graded material (FGM) is considered. The governing equations for a thin cylinder based on the first-order shell theory and Timoshenko's assumptions are obtained. The equations are derived using the Sanders simplified kinematic relations and the principle of work and energy. The constituent mater...

An optimal design of internal pressurized stiffened conical shell is investigated using the genetic algorithm (GA) to minimize the structural weight and to prevent various types of stress and buckling failures. Axial compressive load is applied to the shell. Five stress and buckling failures as constraints are taken into account. Using the discrete elements method as well as the energy method, ...

There have been numerous researchers that have investigated the properties of human intervertebral discs. However, there has been no attempt to characterize the effects of dynamic loading on the compressive stiffness of human lumbar intervertebral discs. Therefore, the purpose of this study was to develop the compressive stiffness properties of lumbar intervertebral discs when subjected to vari...

The gap junction protein, connexin43 (Cx43) is involved in mechanotransduction in bone. Recent studies using in vivo models of conditional Cx43 gene (Gja1) deletion in the osteogenic linage have generated inconsistent results, with Gja1 ablation resulting in either attenuated or enhanced response to mechanical load, depending upon the skeletal site examined or the type of load applied. To gain ...