Background : There is little evidence about the role of Zafirlukast (a highly selective LTD4 antagonist) in Chronic Obstructive Pulmonary Disease (COPD). The Zafirlukast can reduce the need for short-acting rescue β2 agonists, produce fewer exacerbations of asthma and increased quality of life as possible benefits treatment for asthma. The aim of our study was to evaluate the effects of Zafir...

introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...

C pulmonary diseases, a s m a i n l y d e f i n e d b y asthma, bronchiectasis, chronic obstructive lung disease (COPD), interstitial lung disease, pulmonary hypertension etc., represent the third leading cause of death in United States and account for more than 143,382 deaths in 201148. The prevalence of chronic obstructive pulmonary disease (COPD) in India is estimated to be 31.4–57.1% over 6...

Smoking is a risk factor for disease that contributes the most to lung and respiratory diseases. Lung related with cigarette smoke can be classified as COPD (Chronic Obstructive Pulmonary Disease) several types of interstitial such pulmonary langerhans cell histiocytosis, bronchiolitis, desquamative pneumonitis fibrosing disease. This literature review aims shed light not only causes inflammati...

Author details Department of Internal Medicine, Seoul National University College of Medicine, Division of Pulmonary and Critical Care Medicine, Seoul National University Bundang Hospital, 166, Gumi-ro, Bundang-gu, 463-707 Seongnam-si, Gyeonggi-do, Republic of Korea. Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Med...

Overlap syndrome, which is known as the coexistence of chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), was first defined by Flenley. Although it can refer to concomitant occurrence of any of the pulmonary diseases and OSA, overlap syndrome is commonly considered as the coexistence of OSA and COPD. This disease has unique adverse health consequences distinct from ...

APN circulates in different molecular forms in the blood. It has been reported by Miller et al., that by screening bronchoalveolar lavage (BAL) fluids from chronic obstructive pulmonary disease-Emphysema (COPD-E) and control subjects the epithelial cells can also secrete APN. Immuno-histochemistry of lung sections in COPD-E patients’ demonstrated markable levels of adiponectin and adiponectin r...

OBJECTIVES To verify and describe the main events related to the diagnosis and management of chronic obstructive pulmonary diseases in children (COPDC) and adolescents, considering the interrelated physiopathology, genetic, and environmental characteristics. SOURCES Relevant literature from PubMed was selected and reviewed. SUMMARY OF THE FINDINGS COPDC have an environmental and/or genetic ...

There may be an overlap between the clinical pictures of asthma and chronic obstructive pulmonary disease which hampers a clear distinction between the two diseases. Most symptoms presented by patients do not clearly belong exclusively to either asthma or chronic obstructive pulmonary disease. By the nature of their discipline and training, general practitioners focus mainly on symptoms present...

background chronic obstructive pulmonary disease (copd) is a devastating disease.while there is no cure for copd and the lung damage associated with this disease cannot be reversed, it is still very important to diagnose it as early as possible. objectives in this paper, we propose a novel method based on the measurement of air trapping in the lungs from ct images to detect copd and to evaluate...