The outflow system was studied by light microscopy in nine human eyes that were treated with topical timolol maleate (0.5%) prior to enucleation for malignant melanoma of the choroid. The frequency of "giant vacuoles" in the lining endothelium of Schlemm's canal and the diameter of these structures was the same in a control group of eyes as in the timolol-treated series. There was no qualitativ...

In Apterygota muscles are attached to the cuticle by a series of discrete structures. The junction of the muscle and epidermal cells is demarcated by regular interdigitations of the two tissues, with desmosomes lining these processes. Within the epidermal cells, microtubules link up the desmosomes of the interdigitated region with dense material associated with cone-like depressions in the apic...

IN THE BEGINNING the authors discuss the high type of imperforate anus because they say the low type presents "no real problem in achieving continence." They ment ion a report by Partridge and Gough 4 in which they found that "only half the survivors of high anomalies had adequate continence." They say that factors involved in continence are specific sensation of the rectum and anal canal, and ...

Cardiac cushion development provides a valuable system to investigate epithelial to mesenchymal transition (EMT), a fundamental process in development and tumor progression. In the atrioventricular (AV) canal, endocardial cells lining the heart respond to a myocardial-derived signal, undergo EMT, and contribute to cushion mesenchyme. Here, we inactivated bone morphogenetic protein 2 (Bmp2) in t...

Ablation of nonmuscle myosin (NM) II-B in mice during embryonic development leads to marked enlargement of the cerebral ventricles and destruction of brain tissue, due to hydrocephalus. We have identified a transient mesh-like structure present at the apical border of cells lining the spinal canal of mice during development. This structure, which only contains the II-B isoform of NM, also conta...

The aim of the SURICATES (Sediment Uses as Resources in Circular And Territorial EconomieS) Project is to increase sediment reuse for erosion and flood protection. To investigate potential opportunities dredged sediments topsoil following phyto-conditioning, a pilot scale operation was undertaken at Bowling, Scotland. As part normal maintenance, 550 m3 wet removed from Forth Clyde Canal Old Kil...

The compatibility between the used methods of lining for open channels in permeable soils is main indicator about conservation efficiency irrigation water, which means minimizing quantities water losses through transportation process. From this standpoint, and within framework national project rehabilitation canals Egypt, implementing nowadays all over villages Egyptian countryside, work presen...

Cerebrospinal fluid-contacting (CSF-c) cells are found in all vertebrates but their function has remained elusive. We recently identified one type of laterally projecting CSF-c cell in lamprey spinal cord with neuronal properties that expresses GABA and somatostatin. We show here that these CSF-c neurons respond to both mechanical stimulation and to lowered pH. These effects are most likely med...