OBJECTIVE To study the possible effect of angiotensin II type 1 Receptor blocker (AT1 blocker) on renal function, arterial blood pressure and parathyroid hormone related protein over expression in cadmium induced nephrotoxicity in adult male rats. Forty five rats were divided randomly into a control (group I), group II, received cadmium chloride at a dose of 5 mg/kg/day, orally, for nine weeks,...

Nickel and cadmium are heavy metals with some hazards for plant metabolism. The impacts of nickel chloride (0, 400 and 800 μM) in the presence of vitamin B complex (0, 30 and 60 ml from pharmacy commercial stock) and the impacts of cadmium chloride (0, 100, 200, 300, 400, 500 and 600 μl from 100 µM stock) in pot and cadmium nitrate (0, 100, 200, 400, 800, 1600 and 3200 μl from 100 µM stock) in ...

Cadmium is a carcinogen whose genotoxicity is only weak. Besides its tumor-initiating capacity, cadmium may be tumor-promoting, since it interferes with several steps of cellular signal transduction. We have investigated effects of cadmium(II) on protein kinase C (PKC), which is a key enzyme in the control of cellular growth and differentiation. Tumor-promoting phorbol esters cause an activatio...

AIM The main objectives of this study were for comparing the effect of batteries and deep litter rearing systems of domesticated Japanese quail, Coturnix coturnix japonica, on the concentration levels of cadmium, copper, lead, and zinc from the quail meat and offal in Ismailia, Egypt. MATERIALS AND METHODS A total of 40 quail meat and their offal samples were randomly collected from two main ...

Background: Heavy metals such as cadmium (Cd2+) are natural components of the Earth's crust which can not be degraded or destroyed. Industrial, mining and agricultural activities, particularly the excessive use of phosphate fertilizers, have led to high levels of cadmium contamination at many locations worldwide. Some toxic effects of cadmium are due to its inhibition of various enzyme sys...

Diphenylcarbazone has been used for the simultaneous and individual determination of zinc(II) and cadmium(II) at trace levels. The carbazone complexes of zinc(II) and cadmium(II) at pH 7–10 are pink in color, and are soluble in TX-100 micellar media. Under optimum conditions, calibration graphs for individual and simultaneous determination by first, second, third and fourth derivative spectroph...

Two nano-sized mixed-ligand Cd (II) coordination polymers; [Cd (4,4' -bpy) (C4H4O4)].1/4 H2O (1) and[Cd(bpy)1.5 (NO3)2].3H2O (2) (bpy=bipiridine) were synthesized by a sonochemical method and characterized by elemental analyses, thermal gravimetric analysis (TGA), differential thermal analysis (DTA), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR). The cry...

The objective of the current study was to explore the inhibitory effects of quercetin on cadmium-induced autophagy in mouse kidneys. Mice were intraperitoneally injected with cadmium and quercetin once daily for 3 days. The LC3-II/β-actin ratio was used as the autophagy marker, and autophagy was observed by transmission electron microscopy. Oxidative stress was investigated in terms of reactive...

a selective and sensitive method for determination of cadmium and zinc is presented. the method is based on adsorptive accumulation of the complexes of cd (ii) and zn (ii) ions with 4-amiono-5-methyl-2,4-dihydro-3h-1,2,4-triazol-3-tion (mmtt) onto hanging mercury drop electrode (hmde), followed by reduction of the adsorbed species by voltammetric scan using differential pulse modulation. the li...

Experimental data on cadmium (II) and nickel (II) ion sorption on deactivated protonated yeast over a wide range of sorbent and initial metal concentrations, were analyzed by an equilibrium model based on a thermodynamics approach. Model describes relationships between the equilibrium concentration of metal, metal sorption per unit biomass dosage and concentration of sorbent and initial metal c...