Marker assisted selection (MAS) is a tool for breeding, screening, and genetic characterization of germplasm. Allelic variation of both high and low molecular weight glutenin subunits (HMW/LMW-GS) is associated with the rheological properties of wheat flour. In this study, we investigated glutenin pattern using SDS-PAGE and their PCR based on DNA markers in 60 advanced wheat lines and cultivars...

tion of VEGF-D by hypoxia, two VEGF-D promoter fragments, a 3,448-base pair (bp) fragment and a 523-bp fragment, were isolated from a mouse genomic library by genome walking. The fragments were sequenced (GenBank AF345635) and cloned into a pGL3 luciferase reporter vector. The reporter constructs were transfected into rat pulmonary microvascular smooth-muscle cells. Transfection efficiency was ...

To investigate the effects of micronutrients on blood pressure (BP) in patients with type 2 diabetes through a systematic review and meta-analysis, randomized clinical trials (RCTs) of the effects of individual micronutrients on BP in patients with type 2 diabetes were searched in the Medline, Embase, Cochrane, and Clinical Trials.gov databases through April 2016. From the 28,164 studies, 11 RC...

V itamin D deficiency is highly prevalent, with potentially significant consequences for human health. Numerous epidemiological studies have associated vitamin D deficiency with cardiovascular disease and hypertension. However, randomized controlled studies have shown no effect of vitamin D supplementation on blood pressure (BP). Prior studies assessed BP using a peripheral cuff over the brachi...

The decidual/trophoblast PRL-related protein (d/tPRP) is dually expressed by decidual and trophoblast cells during pregnancy. We have characterized the proximal d/tPRP promoter responsible for directing d/tPRP expression in decidual and trophoblast cells. We have demonstrated that the proximal 93 bp of d/tPRP 5'-flanking DNA are sufficient to direct luciferase gene expression in primary decidua...

background: tibolone is frequently used as a hormone-like alternative to traditional hrt. therefore, it is valuable to compare the effects of tibolone and hrt on cardiovascular diseases risk factors.   methods: a total of 156 healthy non-surgical postmenopausal women were included in an open randomized study. they were assigned to receive daily 2.5 mg tibolone plus one cal+d (500 mg calcium and...

UNLABELLED Vitamin D deficiency is a risk factor for arterial hypertension, but randomized controlled trials showed mixed effects of vitamin D supplementation on blood pressure (BP). We aimed to evaluate whether vitamin D supplementation affects 24-hour systolic ambulatory BP monitoring values and cardiovascular risk factors. The Styrian Vitamin D Hypertension Trial is a single-center, double-b...

The study evaluated the association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene (ACE I/D) with self-reported moderate-intensity leisure time physical activity (MILTPA), arterial blood pressure (BP) and history of hypertension (HT). A representative population-based sample of 721 middle-aged adults (358 women) from two areas of Finland was genotyped for the A...

Atopic dermatitis (AD) and bullous pemphigoid (BP) are inflammatory skin diseases associated with intense pruritus significant quality of life (QOL) impact. While they differ in classical presentation (eczematous eruption vs urticaria blisters) population characteristics (young-to middle-aged persons elderly), early stages BP can appear similar to AD clinically histologically. As part this obse...