Objective: To explore the mechanism of circRNA-vgll3 in osteogenic differentiation human bone marrow mesenchymal stem cells. Methods: BMSCs cells were transfected with circRNA-vgll3, and divided into high-level group, low-level negative control group (circRNA-vgll3 not transfected) according to amount transfection. The proliferation apoptosis osteoblasts each analyzed, alkaline phosphatase (ALP...

Biocompatibility and osteoconductivity of porous scaffolds can be improved through coating technique by creating micro- nanostructures on the surfaces. In this study, a biomimetic approach was used to construct bone morphogenetic protein-2 (BMP-2) integrated calcium phosphate (CaP) surface titanium scaffolds. vitro characterizations showed that had mechanical properties comparable those human c...