BACKGROUND Natural foods contain not only nutrients, but also nonnutritious and potentially harmful chemicals. Thus, animals need to evaluate food content in order to make adequate feeding decisions. RESULTS Here, we investigate the effects of acids on the taste neuron responses and on taste behavior of desirable, nutritious sugars and sugar/bitter compound mixtures in Drosophila melanogaster...

Molecular data suggest that receptors for all bitter ligands are coexpressed in the same taste receptor cells (TRCs) while physiological results indicate that individual TRCs respond only to a subset of bitter stimuli. It is also unclear to what extent bitter-responsive neurons are stimulated by non-bitter stimuli. To explore these issues, single neuron responses were recorded from the rat nucl...

Most animals possess taste receptors neurons detecting potentially noxious compounds. In humans, the ligands which activate these neurons define a sensory space called "bitter". By extension, this term has been used in animals and insects to define molecules which induce aversive responses. In this review, based on our observations carried out in Drosophila, we examine how bitter compounds are ...

Two-bottle preference tests were done to determine whether pigs detect bitter-tasting compounds. Four standard bitter compounds and nine bitter-tasting pharmaceutical compounds were tested. Pigs detect and avoid taste compounds that humans perceive as bitter-tasting. A dose-response to varying concentrations of bitter tastants can be measured.

Three experiments were conducted to evaluate the nutritional value of bitter vetch. Experiment 1 was conducted to determine the metabolisable energy content of bitter vetch. Sixteen adult Leghorn roosters were used. Forty grams of bitter vetch were precision-fed individually to 12 roosters. In addition, 4 birds were not fed and served as a control treatment in the measurement of metabolic fecal...

Animals can discriminate among many different types of foods. This discrimination process involves multiple sensory systems, but the sense of taste is known to play a central role. We asked how the taste system contributes to the discrimination of different "bitter" taste stimuli in Manduca sexta caterpillars. This insect has approximately eight bilateral pairs of taste cells that respond selec...

The bitter taste of many protein rich foods resides in the peptide fraction. 61 bitter tasting peptides, isolated from natural systems, and 145 bitter tasting synthetic peptides are reviewed. The relationships between average hydrophobicity and bitter taste are then discussed.

Molecular data suggest that receptors for all bitter ligands are coexpressed in the same taste receptor cells (TRCs), whereas physiological results indicate that individual TRCs respond to only a subset of bitter stimuli. It is also unclear to what extent bitter-responsive neurons are stimulated by nonbitter stimuli. To explore these issues, single neuron responses were recorded from the rat nu...