Boron compounds in the form of boric acid, borax or disodiumoctaborate tetrahydrate have been used as insecticide, fungicide and fire retardant wood preservatives industry for decades. Also, copper is most commonly component relatively modern it highly effective against fungi. The objective this study was to investigate combustion decay resistance boron-copper based solutions which were develop...

New antifungal agents are needed to treat life-threatening fungal infections, particularly with the development of resistance. Surface-active antifungals have the advantages of minimizing host toxicity and the emergence of drug resistance. We have developed a time-dependent drug exposure assay that allows us to rapidly investigate the mechanism of surface-active antifungal drug action. The assa...

OBJECTIVES In order to select new drugs and to predict their in vitro activity against Mycobacterium avium complex (MAC), new quantitative structure-activity relationship (QSAR) models were developed. METHODS The activities against MAC of 29 structurally heterogeneous drugs were examined by means of linear discriminant analysis (LDA) and multilinear regression analysis (MLRA) by using topolog...

We investigated the influences of various reaction conditions on equine herpesvirus type 1 (EHV-1) disinfection by 5 commercial disinfectants (3 quaternary ammonium compounds [QACs] and 2 chlorine-based disinfectants) and 1 anionic surfactant. QACs at their highest recommended concentrations had no virucidal effect on EHV-1 with a 10-min reaction time at 0°C or a 1-min reaction time at room tem...

Biocides are antimicrobial compounds that are widely used in the food industry and medical environments. In this study, we determined the Minimum Inhibitory Concentrations (MICs) by the microdilution method of four different biocides for a large collection of LAB of different origins. The tested isolates belong to 11 species of the Lactobacillus genus and to Streptococcus thermophilus, Streptoc...

The constantly growing resistance of microbes to drugs and other substances which fight microbial infections leads to search for new antimicrobial substances. Among substances which attract the scientists attention are antimicrobial peptides. Such compounds are quite common in nature and belong to the most important elements of the innate immune system of all living organisms. Numerous antimicr...

Quaternary ammonium compounds (QACs) are disinfection agents used in industrial cleaning processes that known to interfere with the proper functioning of anaerobic waste digestion directly impacting quality and quantity biogas produced (i.e., CO2 CH4). While impact these contaminants on digestors well known, have metabolic profile an digestor is less understood. This paper describes use nuclear...

fungicidal efficiency of iranian made benzalkonium chloride named akhgar, afshang and hamoon were evaluated on pure culture species of aspergillus nijer, candida ablicans and mucour according to the standard method no. 2442 issued by the institute of standards and industrial research of iran, from october 1993 to march 1994. suspensions were prepared in a way that each cubic centimeter having 3...

Various amino acid-derived compounds, for example, Nα-Cocoyl-L-arginine ethyl ester (CAE), alkyloxyhydroxylpropylarginine, arginine cocoate, and cocoyl glycine potassium salt (Amilite), were examined for their virucidal activities against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), influenza A virus (IAV), and poliovirus type 1 (PV-1) in comparison to benzalkonium chloride (BKC) and so...