Proton therapy is a rapidly progressing field for cancer treatment. Globally, many proton therapy facilities are being commissioned or under construction. Secondary neutrons are an important issue during the commissioning process of a proton therapy facility. The purpose of this study is to model and validate scanning nozzles of proton therapy at Samsung Medical Center (SMC) by Monte Carlo simu...

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting former clinical pencil beam scanning gantry irradiations ultrahigh dose rates. Methods: PSI Gantry 1 treated patients until December 2018. We optimized the beamline parameters transport 250 MeV extracted from COMET accelerator treatment room, maximizing transmission intensity sample....

Volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) are commonly used treatment techniques for cancer treatment, and both the VMAT and IMRT techniques use the photon beam (mega-voltage X-rays) to deliver radiation dose to the tumor. The capability of modulating radiation beam has increased the ability of delivering more conformal dose distributions to tumor ...

We present a new fast radiotherapy planning algorithm which determines approximatively optimal gantry and table angles, kinds of wedges, leaf positions and intensities simultaneously in a global way. Other parameters are optimized only independently of each other. The algorithm uses an elaborate field management and field reduction. Beam intensities are determined via a variant of a projected N...

The dynamic reliability of the heavy-duty CNC machine tool beam is directly related to machining accuracy which challenging maintain because gantry structure. It important evaluate and components, especially beam. This research investigated a segmented heavy by studying surface morphology joint surface. mechanical model single asperity established based on finite element method. elastic plastic...

Background: Multiple beams are generally used with an increased possibility that the beam axis intersects the treatment table. Treatment tabletops are commonly made of carbon fiber due to its high mechanical strength and rigidity, low specific density, extremely light and low radiation beam attenuation properties. Purpose of this paper is investigated the dose changes in the buildup region and ...

This work investigated the possibility of using proton beam for total body irradia-tion (TBI). We hypothesized the broad-slow-rising entrance dose from a monoen-ergetic proton beam can deliver a uniform dose to patient with varied thickness. Comparing to photon-based TBI, it would not require any patient-specific com-pensator or beam spoiler. The hypothesis was first tested by simulating 250 Me...

Although highly conformal dose distributions can be achieved by IMRT planning, this often requires a large number of segments or beams, resulting in increased treatment times. While flattening-filter-free beams offer a higher dose rate, even more segments may be required to create homogeneous target coverage. Therefore, it is worthwhile to systematically investigate the dependence of plan quali...

PURPOSE The TOPAS Tool for Particle Simulation was developed to make Geant4 Monte Carlo simulation more readily available for research and clinical physicists. Before releasing this new tool to the proton therapy community, several test have been performed to ensure accurate simulations in a variety of proton therapy setups. METHODS TOPAS can model a passive scattering or scanning beam treatm...