INTRODUCTION We present the protocol for a multifactorial intervention study designed to test whether individualised treatment, based on pathophysiological phenotyping and individualised treatment goals, improves type 2 diabetes (T2D) outcomes. METHODS AND ANALYSIS We will conduct a prospective controlled multicentre open-label intervention study, drawing on the longitudinal cohort of the Dan...

3,4-Dichloroaniline (DCA) showed an unusually high bioconcentration factor (BCF) up to 800 in the sediment dweller Lumbriculus variegatus, exceeding BCFs found in fish and other aquatic organisms by a factor of 8–40. In the scope of the European Risk Assessment process for different aromatic amines, concern was expressed with regards to biomagnification and secondary poisoning of man. Although ...

This research investigated four different species of aquatic macrophytes with natural occurrence in an urban environment highly anthropized Southern Brazil. The aim the was to compare phytoremediation potential among E. anagallis, H. grumosa, ranunculoides, and S. montevidensis through Pearson´s correlation analysis cluster analysis, using heavy metal content identified HNO3 - HClO4 indexes. re...

OBJECTIVE To evaluate the effect of liposomes prepared from various natural and synthetic lipids in a rat bladder injury model in the absence or the presence of cholesterol and to elucidate the key structural elements necessary for the efficacy of liposomes required for alleviating bladder hyperactivity. MATERIALS AND METHODS The intravesical pressure was recorded using a transurethral cathet...

background: low back pain caused by work, ranked the second after cardiovascular diseases, are among the most common reasons of patients’ referral to the physicians in iran. this study aimed to determine the changes in back compressive force when measuring maximum acceptable weight of lift in iranian male students. methods: this experimental study was conducted in 2015 on 15 young male students...

Recent detection of fluoxetine in the aquatic environment and fish suggests a possibly high accumulation of fluoxetine; however, no report is available on the bioaccumulation of fluoxetine in aquatic organisms. Since bioaccumulation of fluoxetine was probably dependent on pH near the pK(a) value of 10.1, experiments were conducted approximately at pH 7, 8, and 9. Distribution coefficients betwe...

We investigated the influence of the acanthocephalan parasite Polymorphus minutus on the mortality of its intermediate host, Gammarus roeseli, exposed to cadmium, by the measure of LC(50-96h) values as well as the bioaccumulation of cadmium both in the host and in its parasite. LC(50) results revealed that infected G. roeseli males died less under cadmium stress than uninfected ones; while the ...

Modern chemical legislation requires measuring the bioconcentration factor (BCF) of large numbers of chemicals in fish. The BCF must be corrected for growth dilution, because fish growth rates vary between laboratories. Two hypotheses were tested: (1) that BCFs of multiple chemicals can be measured simultaneously in one experiment, and (2) that internal benchmarking using a conservative test su...