BACKGROUND Studies performed over the past decade have identified fairly consistent epidemiological patterns of risk factors for visceral leishmaniasis (VL) in the Indian subcontinent. METHODS AND PRINCIPAL FINDINGS To inform the current regional VL elimination effort and identify key gaps in knowledge, we performed a systematic review of the literature, with a special emphasis on data regard...

thirty eight patients with visceral leishmaniasis were reviewed, age ranged from 2 months to 10 years, 74% above 3.5 y, with 24% affection in infants (7 to 12 m), with slight male predilection. all the patients had weight loss, splenomegaly and hepatomegaly, 97% with fever, 92% had positive serology and 63% had positive bone marrow findings. a few patients presented with atypical clinical findi...

in a descriptive analytical study in six villages in meshkin shahr area, the important endemic focus of kala-azar in northwest iran, a kap study was carried out on various aspects of kala-azar in a total of 245 young mothers selected randomly and interviewed the results of the present investigation showed that 93.5% of the mothers were illiterate and only 2.4% of them had acceptable knowledge a...

The Fucose-Mannose Ligand (FML) of Leishmania donovani is a complex glycoproteic fraction. Its potential use as a tool for diagnosis of human visceral leishmaniasis was tested with human sera from Natal, Rio Grande do Norte, Brazil. The FML-ELISA test, showed 100% sensitivity and 96% specificity, identifying patients with overt kala-azar (p < 0.001, when compared to normal sera), and subjects w...

Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we report an 11 month-old male infant with diagnosis of kala-azar who presented with pallor, hepatosplenomegaly, failure to gain weight, and no history of fever. Surprisingly, fever started after beginning of ...

Introduction.?About eighteen months ago, we (Napier and Sen, 1940) published a preliminary paper on the treatment of kala-azar by 4 : 4'-diamidino stilbene. At the time our paper was sent to press, there were in the literature? that had arrived in this country?only two detailed reports on cases treated by this drug (Adams and Yorke, 1939; and Adler and Rachmilewitz, 1939). Since then a small sp...

Clinically visceral leishmaniasis is suspected in only a fraction of infected persons, as the majority of these may not have clinical manifestations and remain asymptomatic. There is scanty information on diagnosing latent infections and predicting disease in asymptomatic persons. We therefore carried out a study on asymptomatic contacts of patients with visceral leishmaniasis and post-kala-aza...