Angiotensin-converting enzyme-2 (ACE-2) is an essential element in the renin-angiotensin RAS system and plays a key role coronavirus entrance to human body attachment cell. Variation ACE-2 may increase capability of binding with tissues lead variation disease severity among patients. For this reason, study aimed take some SNPs different COVID-19 patient cases show possible Angiotensin-Convertin...

In the present study, we assessed the role of tissue angiotensin-converting enzyme as a determinant of intrarenal hemodynamics by using the angiotensin-converting enzyme inhibitor trandolaprilat and the angiotensin II receptor antagonist losartan. Afferent and efferent arteriolar diameters were measured with computer-assisted vessel imaging in isolated perfused hydronephrotic rat kidneys. In re...

Serum angiotensin converting enzyme activities were estimated during pregnancy and the puerperium in a woman with sarcoidosis and a series of normal women. In the patient with sarcoidosis angiotensin converting enzyme activity was raised during pregnancy, particularly at 21 weeks' gestation, yet she remained well with no symptoms to suggest relapse of sarcoidosis. Serum angiotensin converting e...

The paper presents the theoretical considerations on role of endocrine and metabolic alterations accompanying COVID-19 infection. These may be presumed basis following two observations. Firstly, virus SARS-CoV-2 responsible for infection uses an important renin–angiotensin system (RAS) element — angiotensin-converting enzyme 2 (ACE2) as a receptor protein entry into target cells and, in consequ...

Literature data on the role of renin-angiotensin-aldosterone system in pathogenesis arterial hypertension and angiotensin-converting enzyme inhibitors treatment have been given.The is central element controlling body's water-salt balance blood pressure. The main effector link renin-angiotensin angiotensin II, which causes vasospasm, activates heart contraction, inhibits production bradykinin, p...