Most primary CNS tumors are astrocytic tumors. Glial classified according to histological criteria. The WHO classification for malignant gliomas in adults includes grades II through IV. Terms that classify grade astrocytomas (A), oligodendrogliomas (ODG), or mixed (GM). Grade III named similarly, and preceded by the word anaplastic, example, anaplastic astrocytoma (AA), oligodendroglioma (ODGA)...

The clinical significance of anaplastic features, a rare event in pilocytic astrocytoma (PA), is not fully established. We reviewed 34 PA with anaplastic features (Male = 21, Female = 13; median age 35 y, 5 to 75) among approximately 2200 PA cases (1.7%). Tumors were included which demonstrated brisk mitotic activity [at least 4 mitoses/10 high power fields (400 x )], in addition to hypercellul...

Anaplastic glioma (AG) is divided into three morphology-based groups (anaplastic astrocytoma, anaplastic oligodendroglioma, anaplastic oligoastrocytoma) as well as three molecular groups (glioma-CpG island methylation phenotype [G-CIMP] negative, G-CIMP positive non-1p19q codeleted tumors and G-CIMP positive codeleted tumors). The RTOG 9402 and EORTC 26951 trials established radiotherapy plus (...

Acquired (neurogenic) stuttering is a rare phenomenon seen after cerebral infarction or brain injury. Aetiology of this symptom is unclear, but recent evidence supports that it is a disturbance in the left hemispheric neural network involving the interplay between the cortex and basal ganglia. We present the case of a patient who develops acquired stuttering after a recurrence of a right tempor...

Dra. Martha Tena-Suck – Departamento de Neuropatología / Instituto Nacional de Neurología y Neurocirugía “Manuel Velasco Suárez” Av. Insurgentes Sur, 3788 Col. La fama, Delegación Tlalpan C.P. 14269 México DF México. E-mail: [email protected] Intracranial germ cell tumors (GCTs), especially pineal tumors have attracted the special attention of neuropathologists and neurosurgeons because of ...