f is now well established that agglutinins 0r V. cholera develop in the blood of cholera Patients a few days after the onset of the ^ease. Greig (1914) has credited two French observers, Achard and Bensaude, with having been the first to discover, in 1897, these specific ^Sglutinins in the blood of cholera patients. rreig examined the blood of 363 persons, who lad been attacked by cholera, and ...

1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected wi...

A method was described for the partial purification of beta galactosidase and beta glucosaminidase from Clostridium tertium culture supernatants. Treatment of erythrocytes with preparations containing both enzymes decreases their ability to react with anti-I cold agglutinins, and with Type XIV antipneumococcal horse serum. Erythrocytes of blood group A(1) are altered more rapidly and extensivel...