This paper summarizes assessment biochemical markers of the development hepatitis B viruses (HBV), in which any possible connection between certain parameters and chronic was identified. Liver function tests are helpful diagnosing liver disease dysfunction, assessing severity, tracking treatment, determining prognosis. According to findings studies, patients have higher levels ALP, GPT, GOT, TS...

Intravenous methylprednisolone (IVMP) pulse therapy is the first-line treatment for the active phase of moderate to severe Graves' orbitopathy (GO). However, acute and severe liver damage has been reported during and after IVMP therapy. In this retrospective study, we investigated risk factors for liver dysfunction during and after IVMP therapy based on 175 Japanese patients with moderate to se...

A novel coronavirus (severe acute respiratory syndrome [SARS-CoV-2]), has been causing a COVID-19 pandemic of in humans since December 2019. It appears to be similar structure the virus that caused SARS-CoV outbreak 18 years ago. However, addition disorders, patients might suffer extra-pulmonary including gut dysfunction or liver complications, which show as gut–lung crosstalk. Fecal specimens ...

The nonsteroidal antiandrogenic drug flutamide [4'-nitro-3'-(trifluoromethyl)isobutyranilide] is a safe and generally well-tolerated drug used for the treatment of prostate cancer. We describe the case of a 74-year-old male who developed life-threatening acute liver failure during flutamide therapy. Other causes of acute liver failure were appropriately ruled out and there was no evidence of ac...

Acute graft-versus-host disease (GVHD) is a major complication of bone marrow transplantation (BMT) and is characterized by hematopoietic dysfunction, immunosuppression, and tissue injury in the skin, liver, and intestinal mucosa. Hepatocyte growth factor (HGF), originally identified and cloned as a potent mitogen for hepatocytes, induces mitogenic and antiapoptotic activity in various epitheli...

conclusions fulminant hepatitis b is associated with distinct mutational patterns of hbv, underlining that genomic diversity of the virus is an important factor determining its pathogenicity. results the most commonly detected diversities affect regulatory motifs of hbv in the core and s region, indicating that these alterations may convert the virus to an aggressive strain. moreover, mutations...