The growth rate of Sarcoma 180 and of a mammary adenocarcinoma in potassium deficient mice did not significantly differ from that in pair-fed control mice. The po tassium concentration of these tumors in potassium-deficient mice was the same as in the control mice, although the potassium concentration of muscle and plasma was only half of that in the controls. The in vivo equilibration of K@ in...

Using standard WHO methodology, this study investigated the susceptibility of 4th instar Aedes aegypti (L) and Culex annulirostris (Skuse) larvae to three extracts from Callitris glaucophylla (J. Thompson & L. Johnson) (1: steam distillation extract, 2: liquefied refrigerant gas extract, and 3: methanol reflux extract), lambda-cyhalothrin (a synthetic pyrethroid insecticide) and fenitrothion (a...

Aim: Silicosis has long been recognized as an important occupational lung disease that is included in the group of pneumoconiosis. As already well-known silicosis a progressive pneumoconiosis characterized by fibrosis lungs. Also, chronic exposure to silica may cause obstructive pulmonary disease, emphysema, cancer, and fibrosis. Asymmetric dimethyl arginine (ADMA), symmetric (SDMA), L-NMMA (NG...

The antitumor effects of methotrexate with 5-fluorouracil against the Sarcoma 180 mouse tumor model were found to be schedule dependent. Pretreatment of tumor-bearing animals with methotrexate significantly enhanced the antitumor activity of the combination relative to simultaneous treatment or to those with methotrexate following 5-fluorouracil. These studies indirectly support the hypothesis ...

It has been demonstrated that cells killed by heat or irradiation have four times greater affinity for actinomycin D (AMD) than do viable tumor cells. By using a double labeling technique, we were able to show that, with increasing amounts of AMD bound in cells, the incorporation of RNA precursors is proportionally decreased. However, in the presence of nonviable cells or of native DNA, the AMD...