Objective: To investigate the feasibility of hippocampal-sparing whole-brain radiotherapy and reduction in neurocognitive function impairment after radiotherapy. Methods: Forty-three patients with brain metastases were selected. Whole-brain radiotherapy was performed in 22 patients, with 3-dimensional conformal radiotherapy in parallel opposed fields. Twenty-one patients had significant differe...

background: radiotherapy plays an important role in the management of most malignant and many benign primary central nervous system (cns) tumors. radiotherapy affects both tumor cells and uninvolved normal cells; so, it is important to estimate absorbed dose to organs at risk in this kind of treatment. the aim of this study was to determine the absorbed dose to chiasma, lens, optic nerve, retin...

This article presents methods and results of surgery and radiotherapy of brain metastases from non-small cell lung cancer (BMF-NSCLC). Patients with single BMF-NSCLC, with Karnofsky score ≥ 70 and controlled extracranial disease are the best candidates for surgery. Stereotactic radiosurgery (SRS) is recommended in patients with 1-3 BMF-NSCLC below 3-3.5 cm, with minor neurological symptoms, loc...