OBJECTIVE To evaluate neonatal outcome in Kell haemolytic disease compared to Rh D haemolytic disease. STUDY DESIGN Retrospective study of all (near)-term neonates with Kell (n=34) and Rh D haemolytic disease (n=157) admitted to our centre between January 2000 and December 2008. We recorded the need for exchange transfusion and top-up transfusions up to 3 months of age. RESULTS Neonates in ...

During a five and a half year period, exchange transfusions were performed through the peripheral vessels in 201 of the 214 infants (94%) who required either double volume or partial plasma exchange transfusions. Peripheral vessel exchange transfusion is simple, practicable, and safe with few complications. Technical difficulties in catheterizing the peripheral artery and vein may be overcome b...

BACKGROUND An exchange transfusion involves replacing patient's blood with donor blood in order to remove abnormal blood components and circulating toxins while maintaining adequate circulating blood volume. OBJECTIVE To observe the incidence, causes of jaundice requiring Exchange and any adverse event of exchange transfusion in newborns with unconjugated hyperbilirubinemia. METHOD Prospect...

Exchange blood transfusion in cases of erythroblastosis foetalis is now an accepted form of treatment but a somewhat tedious one, especially if it has to be carried out in the early hours of the morning. It was, therefore, decided to try and see whether the time could be cut down by using two syringes, whereby blood was withdrawn from the infant into one while the other was being charged with b...

The regulation of iron supply to plasma was studied in male rate. Repeated exchange transfusions were first carried out with plasma from iron-deficient or iron-loaded animals. There was no recognizable effect on the amount of iron entering the plasma as evidenced by plasma iron concentration or iron absorption by recipient animals. In other studies, iron compounds having different tissue distri...

Exchange transfusion of blood (75-80% replacement of blood of recipient animals) was used to study the effect of blood-borne influences on nuclear labeling with thymidine-3H and on occur rence of mitosis in hepatocytes of rat liver. Intact or shamhepatectomized rats and partially hepatectomized rats were: (a) not transfused, (6) transfused with blood from rats with intact livers, or (c) transfu...

Isolation of polymorphonuclear leukocytes (PMN) provides an opportunity to study PMN activity in vitro and to label PMN for study of in vivo kinetics. However, simple phlebotomy (SP) of a small animal frequently yields too few PMN for in vitro handling, while PMN harvested from an induced-peritonitis may not accurately reflect PMN in a less stimulated state. We report a novel method of harvesti...

background: acute normovolemic hemodilution is an available technique to decrease the side effects of allogenic blood transfusion. the aim of this study was to compare acute normovolemic hemodilution with allogenic blood transfusion in adult patients who were scheduled for femoral fracture surgery. methods: in this randomized controlled trial, 50 patients were randomly allocated into two equal ...

BACKGROUND In Myanmar, approximately half of all neonatal hospital admissions are for hyperbilirubinaemia, and tertiary facilities report high rates of Exchange Transfusion (ET). The aim of this study was to evaluate the effectiveness of the pilot program in reducing ET, separately of inborn and outborn neonates. METHODS The study was conducted in the Neonatal Care Units of four national tert...